Evidence map›Paper›PMID 42037932›Full record

ArticleCureus2026

Senna Laxative-Associated Severe Ischemic Bowel Disease in an 87-Year-Old Patient: A Clinical Warning.

D I He, Lin Liu, Xiangmei Duan, Wenyong Shen, Jianhua Shi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D I HeInternal Medicine Department, Fuling Hospital Affiliated to Chongqing University, Chongqing, CHN.
Lin LiuGastroenterology Department, Fuling Hospital Affiliated to Chongqing University, Chongqing, CHN.
Xiangmei DuanGastroenterology Department, Fuling Hospital Affiliated to Chongqing University, Chongqing, CHN.
Wenyong ShenGastroenterology Department, Fuling Hospital Affiliated to Chongqing University, Chongqing, CHN.
Jianhua ShiGastroenterology Department, Fuling Hospital Affiliated to Chongqing University, Chongqing, CHN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Senna laxative, one of the major stimulant laxatives, has received less attention regarding its potential risk of intestinal ischemia in the elderly population. An 87-year-old female with a past medical history of chronic constipation developed abdominal pain and fever after oral ingestion of senna laxative for constipation and was subsequently diagnosed with ischemic bowel disease upon hospitalization. Symptomatic and supportive treatment, such as antibiotics, acid inhibition and stomach protection, fluid replenishment, and intravenous nutrition, was given. After treatment, the patient's condition stabilized, her symptoms improved, and she was allowed to leave the hospital. This case highlights that the use of senna laxative in elderly patients may lead to severe ischemic intestinal disease. Clinicians should be vigilant about the adverse reactions of senna laxative in elderly patients.

Indexed as

anthraquinoneischemic colitislaxative abusesenna laxativesenna side effects

Identifiers

PMID42037932
PMCPMC13110063

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.