Evidence map›Paper›PMID 42037878›Full record

ArticleCureus2026

A Novel Intraoral Technique for Botulinum Toxin Type A Application in the Mentalis Muscle.

Saverio Lembo, Paola Macias-Arias, Maria Paulina Uribe Posada, Raul Banegas, Jaime Rengifo

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saverio LemboAnatomy and Head and Neck Surgery, Hospital of San Miguel, Buenos Aires, ARG.
Paola Macias-AriasDermatology, Federico Lleras Acosta ESE University Hospital Dermatological Center, Bogota, COL.
Maria Paulina Uribe PosadaDermatology, Private Practice, Medellin, COL.
Raul BanegasPlastic Surgery, Private Practice, Buenos Aires, ARG.
Jaime RengifoDermatology, Pontifical Bolivarian University, Medellin, COL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mentalis muscle plays a critical role in lower facial balance by stabilizing the lower lip and shaping the chin contour. Botulinum toxin type A (BoNT-A) is commonly used to manage excessive mentalis activity; however, inaccurate injection techniques may lead to functional impairment and undesirable aesthetic outcomes. This technical report describes a novel and innovative intraoral botulinum toxin injection technique targeting the mentalis muscle based on precise anatomical localization of its origin. The proposed method introduces a new intraoral approach designed to improve injection accuracy while minimizing toxin diffusion and preserving lower lip function. A detailed anatomical assessment was performed to define the muscle's origin, fiber orientation, and relevant surface landmarks, which informed the development of a controlled injection strategy emphasizing precise depth and placement. In clinical application, the technique was performed in three patients, demonstrating consistent modulation of mentalis contraction, improvement in chin surface appearance, and preservation of lower lip function without functional compromise. This new and reproducible technique highlights the importance of anatomical precision in BoNT-A injection planning and provides a practical framework to enhance safety and aesthetic outcomes in treatments of the lower third of the face.

Indexed as

anatomical approachbotulinum toxin type achin contouringintraoral injection techniquementalis muscle

Identifiers

PMID42037878
PMCPMC13104702

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.