ArticleCureus2026
Low-Proliferative Invasive Mucinous Carcinoma of the Breast in an Octogenarian: A Case Report Highlighting Pathology-Guided De-escalation.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Invasive mucinous carcinoma (IMC) is an uncommon histologic subtype of breast cancer characterized by abundant extracellular mucin and generally indolent behavior. It occurs more frequently in older women and is often associated with favorable prognostic features.An 84-year-old woman with no prior history of breast malignancy was found to have a suspicious lesion in the upper outer quadrant of the left breast on routine imaging. Ultrasound-guided core needle biopsy demonstrated IMC, Grade I/III, involving all four cores, with the largest contiguous tumor focus measuring 1.3 cm. Immunohistochemistry showed strong estrogen receptor positivity (95%), progesterone receptor positivity, human epidermal growth factor receptor 2 negativity (1+), and an extremely low Ki-67 proliferation index (~1%). Pathologic processing met established fixation standards.This case highlights the importance of histologic subtype and proliferative activity in guiding risk stratification and management considerations for breast cancer in elderly patients. Recognition of indolent tumor biology may help avoid overtreatment while maintaining oncologic safety.
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