ArticleFrontiers in neurology
Cortical activation patterns mediating motor recovery: a randomized controlled fNIRS study of rTMS-integrated dual-task training in stroke survivors.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stroke remains a leading cause of long-term disability worldwide, imposing a substantial burden on individuals and healthcare systems. The recovery of gait and balance is often hindered by cognitive-motor interference, necessitating effective rehabilitation strategies. Objectives: We aimed to evaluate the synergistic efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with cognitive-motor dual-task training on lower limb motor recovery in stroke survivors. Methods: A total of 150 stroke survivors were randomized into three groups: the single-task walking group (Group 1, Results: A two-way repeated measures ANOVA revealed a highly robust group × time interaction ( Conclusion: The integration of rTMS with cognitive-motor dual-task training yields superior improvements in gait speed, stride mechanics, and balance compared to conventional therapies. This enhanced recovery is mechanistically supported by the upregulation of the supplementary motor area (SMA), suggesting that rTMS facilitates the central reorganization required for complex motor planning in concert with improved gait execution.
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