ArticleJournal of research in pharmacy practice2026
Medication Adherence and Clinical Outcomes among Patients with Chronic Kidney Disease: A 6-month Prospective Evaluation using Individual Adherence Assessment.
Article in Journal of research in pharmacy practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Medication adherence is a critical issue in managing chronic kidney disease (CKD) patients for slowing CKD progression. Objective: The aim of this study was to evaluate the relationship between individual medication adherence and secondary clinical outcomes (pill burden, medication knowledge, and CKD stages) over a 6-month period. This prospective observational study with repeated measures was performed among patients with CKD in a tertiary hospital in Malaysia. Methods: A prospective observational study was conducted among CKD patients, with assessments at baseline, month 3, and month 6. Individual adherence, pill burden, medication knowledge, and CKD stages were assessed at each visit. Groups were compared using Mann-Whitney Findings: A total of 200 patients were included, with 140 completing the 6-month follow-up. Medication adherence remained stable over time, with 58.0% ( Conclusion: These findings highlight the clinical value of pharmacist-led, medication-level adherence assessment, enabling targeted interventions to optimize therapy, reduce complications, and improve patient outcomes.
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