ArticleCardiology and cardiovascular medicine2026
Most Effective Interventions for Improving Upper Extremity Function in Patients with Hemiparesis.
Article in Cardiology and cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Door-to-Needle Optimization in Acute Ischemic Stroke: A Review of Rapid Emergency Department Interventions.Cardiology and cardiovascular medicine · 2026Article
- Robotic Cholecystectomy: Outcomes, Safety, and Value in the Era of Advanced Technology.Journal of surgery and research · 2026Article
- Critical Assessment of Optimal Timing to Initiate Post-Stroke Rehabilitation.Archives of internal medicine research · 2026Article
- Stiff Person Syndrome: Bridging Neuroimmunology and Rehabilitation for Improved Patient Outcomes.Archives of internal medicine research · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Hemiparesis, commonly resulting from stroke, leads to significant impairments in upper extremity function, limiting daily activities and reducing quality of life. Effective rehabilitation strategies are essential to enhance motor recovery and restore functional independence. This review evaluates the most effective interventions for improving upper extremity function in patients with hemiparesis. A comprehensive literature review was conducted, analyzing systematic reviews, randomized controlled trials, and clinical guidelines. The efficacy of various interventions, including task-specific training, constraint-induced movement therapy (CIMT), neuromuscular electrical stimulation (NMES), mirror therapy, virtual reality, bilateral arm training, pharmacological approaches, and robotic-assisted rehabilitation, was assessed based on their impact on motor function and daily activities. The review highlights the role of neuroplasticity in motor recovery, emphasizing interventions that promote cortical reorganization. Task-specific training, CIMT, and NMES demonstrate strong evidence in enhancing motor function. Emerging technologies, such as brain-computer interfaces and robotics, show promise in optimizing rehabilitation outcomes. Factors influencing recovery, including stroke severity, time since onset, and patient motivation, are discussed. Studies consistently support the effectiveness of CIMT and task-specific training in improving upper extremity function. NMES and mirror therapy are beneficial adjunct therapies, particularly for patients with moderate impairment. Virtual reality and robotics enhance engagement and motor learning, while pharmacological and stem cell therapies are emerging areas with potential but require further research. A multimodal rehabilitation approach combining task-oriented therapies, neuromodulation, and emerging technologies yields the best outcomes for upper extremity recovery in hemiparesis patients. Future research should focus on optimizing individualized treatment plans and integrating novel therapeutic modalities to maximize functional gains.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.