ArticleJournal of virology2026
PTBP1 is upregulated in response to Zika virus infection and restrains viral replication by hijacking viral NS1 protein to induce NS1 degradation.
Menglan Rao, Yue Kong, Shuang Liu, Zicong Chen, Jiuxiu Lin, Yicong Liang, Zhiwei Lei, Zhen Luo
Abstract read
In one paragraphArticle in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Menglan Rao *Institute of Medical Microbiology, Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou, China.
Yue Kong *Department of Microbiology and Immunology, Basic Medicine College, Jinan University, Guangzhou, China.
Shuang Liu *Institute of Medical Microbiology, Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou, China.
Zicong ChenInstitute of Medical Microbiology, Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou, China.
Jiuxiu LinDepartment of Microbiology and Immunology, Basic Medicine College, Jinan University, Guangzhou, China.
Yicong LiangInstitute of Medical Microbiology, Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou, China.
Zhiwei LeiDepartment of Gastroenterology, Affiliated Qingyuan Hospital, Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, China.ORCID 0000-0002-9406-2127 Zhen LuoInstitute of Medical Microbiology, Department of Immunology and Microbiology, College of Life Science and Technology, Jinan University, Guangzhou, China.ORCID 0000-0002-1142-2845 Funding
Guangdong Basic and Applied Basic Research Foundation 2025A1515012441National Natural Science Foundation of China 32400132Open Research Project of the Key Laboratory of Viral Pathogenesis & Infection Prevention and Control of the Ministry of Education 2024VPPC-R08
6 · The paper itselfAbstract
Zika virus (ZIKV), belonging to the
Indexed as
Heterogeneous-Nuclear RibonucleoproteinsPolypyrimidine Tract-Binding ProteinViral Nonstructural ProteinsVirus ReplicationZika VirusZika Virus InfectionAnimalsChlorocebus aethiopsHEK293 CellsHumansHypoxia-Inducible Factor 1, alpha SubunitProteolysisUp-RegulationVero CellsHeterogeneous-Nuclear RibonucleoproteinsHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitNS1 protein, zika virusPolypyrimidine Tract-Binding ProteinPTBP1 protein, humanViral Nonstructural Proteinshypoxia-inducible factor-1αlysosomal pathwaynon-structural protein 1polypyrimidine tract-binding protein 1Zika virus
Identifiers
PMID42037413
PMCPMC13185633
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