Evidence map›Paper›PMID 42037396›Full record

ArticleAntimicrobial agents and chemotherapy2026

Restoration of daptomycin sensitivity with adjunctive cefazolin is associated with C-terminal MprF mutations in MRSA bacteremia isolates.

Kathleen P Davis, Husain Poonawala, Connor Murphy, Cheleste Thorpe, Adriana Rosato, Bree B Aldridge

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kathleen P DavisStuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Boston, Massachusetts, USA.ORCID 0000-0002-3034-2162
Husain PoonawalaStuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Boston, Massachusetts, USA.ORCID 0000-0003-4334-7226
Connor MurphyMaine Health Institute for Research, Scarborough, Maine, USA.ORCID 0000-0001-6533-3920
Cheleste ThorpeStuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Boston, Massachusetts, USA.ORCID 0000-0002-6476-3037
Adriana RosatoStuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Boston, Massachusetts, USA.ORCID 0000-0001-6115-6955
Bree B AldridgeStuart B. Levy Center for Integrated Management of Antimicrobial Resistance, Boston, Massachusetts, USA.ORCID 0000-0003-2236-1424

Funding

CTSA K12 Program at Tufts UniversityK12TR004384 · NCATS · TUFTS UNIVERSITY BOSTON · PI Karen Freund, Lesley Ann Inker · 2023 to 2026
$6.1M
NCATS NIH HHS K12 TR004384NIH HHS K12TR004384
6 · The paper itself

Abstract

Daptomycin (DAP) or vancomycin (VAN) resistance can result in methicillin-resistant

Indexed as

AminoacyltransferasesAnti-Bacterial AgentsBacteremiaBacterial ProteinsCefazolinDaptomycinMethicillin-Resistant Staphylococcus aureusFirst Generation CephalosporinsHumansMicrobial Sensitivity TestsMutationStaphylococcal InfectionsVancomycinAminoacyltransferasesAnti-Bacterial AgentsBacterial ProteinsCefazolinDaptomycinFirst Generation CephalosporinsmprF protein, Staphylococcus aureusVancomycincefazolindaptomycinMRSAmultiple peptide resistance factor (MprF)vancomycin

Identifiers

PMID42037396
PMCPMC13231919

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.