Difficult-to-treat resistance (DTR), treatment, and outcomes of carbapenem-resistant Enterobacterales infections in the setting of IMP-type carbapenemase predominance in Japan.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
22 authors.
Koji OhyamaDepartment of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.ORCID 0000-0002-8472-0413
Kohei UemuraBiostatistics and Bioinformatics Course, The University of Tokyo, Bunkyo City, Tokyo, Japan.
Yasufumi MatsumuraDepartment of Clinical Laboratory Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-8595-8944
Ryota HaseDepartment of Infectious Diseases, Japanese Red Cross Narita Hospital, Narita, Chiba, Japan.ORCID 0000-0002-3135-1757
Hideaki KatoInfection Prevention and Control Department, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Takashi MatonoDivision of Infectious Disease and Hospital Epidemiology, Saga University Hospital, Saga, Japan.ORCID 0000-0001-9957-0510
Naoya ItohDepartment of Infectious Diseases, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Aichi, Japan.ORCID 0000-0001-6269-7884
Takehiro HashimotoHospital Infection Control Center, Oita University Hospital, Yufu, Oita, Japan.
Go YamamotoDepartment of Infection Control and Prevention, Osaka University Hospital, Suita, Osaka, Japan.ORCID 0009-0000-8007-3215
Momoko MawatariDepartment of Infectious Diseases, Japanese Red Cross Medical Center, Shibuya, Tokyo, Japan.
Takeya TsutsumiDepartment of Infectious Diseases, The University of Tokyo Hospital, Bunkyo City, Tokyo, Japan.ORCID 0000-0003-0851-1887
Tetsuya SuzukiDepartment of Infection Control and Prevention, University of Yamanashi Hospital, Chuo City, Yamanashi, Japan.ORCID 0000-0003-3165-9062
Masahiro SuzukiDepartment of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.ORCID 0000-0003-4550-3499
Takuya HosodaDepartment of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
Aki SakuraiDisease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku City, Tokyo, Japan.ORCID 0000-0003-2198-8954
Yusuke AsaiAMR Clinical Reference Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku City, Tokyo, Japan.ORCID 0000-0003-2979-3449
Shinya TsuzukiDisease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku City, Tokyo, Japan.ORCID 0000-0001-5732-846X
Kayoko HayakawaDisease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku City, Tokyo, Japan.ORCID 0000-0002-5480-4405
David van DuinDivision of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.ORCID 0000-0003-4784-3227
Norio OhmagariDisease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku City, Tokyo, Japan.ORCID 0000-0002-4622-8970
Yohei DoiDepartment of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.ORCID 0000-0002-9620-2525
Sho SaitoDisease Control and Prevention Center, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku City, Tokyo, Japan.ORCID 0000-0002-9981-7584
Funding
Japan Society for the Promotion of Science JP19K19450Japan Society for the Promotion of Science JP22K17408NCGM Intramural Research Fund 22A1007Shionogi
6 · The paper itself
Abstract
Carbapenem-resistant Enterobacterales (CRE) pose a global threat due to limited treatment options and high mortality. Difficult-to-treat resistance (DTR), defined as non-susceptibility to all conventional β-lactams and fluoroquinolones, has primarily been applied to
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Difficult-to-treat resistance (DTR), treatment, and outcomes of carbapenem-resistant Enterobacterales infections in the setting of IMP-type carbapenemase predominance in Japan. · full record | OpenQuestion