Evidence map›Paper›PMID 42037360›Full record

ArticleMicrobiology resource announcements2026

Human astrovirus draft genomes from under-five children presenting with gastroenteritis in Malawi from 2012 to 2024.

Ernest Matambo, Flywell Kawonga, Chimwemwe Mhango, End Chinyama, Josephine Msowoya, Clara Majengo, Ayodeji E Ogunbayo, Nkosazana Shange, Hlengiwe Sondlane, Milton T Mogotsi and 8 more

Abstract read
In one paragraph

Article in Microbiology resource announcements, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ernest MatamboDepartment of Pharmacy, School of Life Sciences and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi.ORCID 0009-0000-8428-4036
Flywell KawongaMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.ORCID 0009-0000-7105-5015
Chimwemwe MhangoMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.ORCID 0000-0002-8769-7730
End ChinyamaMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.
Josephine MsowoyaMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.
Clara MajengoMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.
Ayodeji E OgunbayoNext Generation Sequencing Unit, School of Biomedical Sciences and Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Nkosazana ShangeNext Generation Sequencing Unit, School of Biomedical Sciences and Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Hlengiwe SondlaneNext Generation Sequencing Unit, School of Biomedical Sciences and Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Milton T MogotsiNext Generation Sequencing Unit, School of Biomedical Sciences and Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Francis E DennisDepartment of Electron Microscopy and Histopathology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Accra, Ghana.
Prisca Benedicto MatamboMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.
Arox W Kamng'onaBiomedical Sciences Department, School of Life Sciences and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi.
Benjamin KumwendaBiomedical Sciences Department, School of Life Sciences and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi.
Martin M NyagaNext Generation Sequencing Unit, School of Biomedical Sciences and Division of Virology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Celeste M DonatoEnteric Diseases Group, Murdoch Children's Research Institute, Parkville, Melbourne, Australia.
Chrispin ChaguzaInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Khuzwayo C JereMalawi-Liverpool-Wellcome Programme, Queen Elizabeth Central Hospital Campus, Blantyre, Malawi.

Funding

Bill and Melinda Gates Foundation INV-046917
6 · The paper itself

Abstract

Human astroviruses (HAstVs) account for 2% to 9% of gastroenteritis cases in children and are occasionally associated with central nervous system complications. We report six draft HAstV genomes from Malawian children <5 years old with gastroenteritis, providing baseline information for the understanding of HAstV diversity and disease burden in sub-Saharan Africa.

Indexed as

astrovirusdraft genomesgastroenteritisMalawi

Identifiers

PMID42037360
PMCPMC13248679

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.