ArticleTurkish journal of ophthalmology2026
Effect of Accelerated Epi-Off Crosslinking on Optical Quality, Corneal Aberrations, and Epithelial Wavefront During Adolescence.
Article in Turkish journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To examine the effect of accelerated epi-off crosslinking (A-CXL) on visual acuity and quality in adolescent patients with progressive keratoconus. Materials and Methods: The study included 109 eyes of 109 patients (mean age 16.24±2.55 years). MS-39 anterior segment optical coherence tomography images from before A-CXL and 1 month, 6 months, and 12 months after A-CXL were analyzed. Corneal tomographic parameters, total corneal aberrations, corneal epithelial aberrations, and optical quality indicators such as modulation transfer function (MTF) and Strehl ratio of the point spread function (PSF) were recorded. Results: A significant improvement in corrected distance visual acuity was observed at 6 and 12 months after A-CXL (0.23±0.10 and 0.22±0.10 logarithm of the minimum angle of resolution [logMAR]) compared to the pre-A-CXL value (0.30±0.12 logMAR) (p<0.001 for both). MTF-5 and MTF-15 values were significantly higher at 12 months after A-CXL compared to before A-CXL (p<0.001). However, almost all MTF and PSF values were significantly lower at 1 month after A-CXL than at the other visits (p<0.05). Significant improvements were seen in root mean square higher-order aberrations (RMS-HOAs), vertical coma, and vertical trefoil values at 12 months after A-CXL compared to before A-CXL. A significant improvement was also detected in corneal epithelial aberrations, specifically in the vertical coma value. The change in corrected distance visual acuity at 12 months after A-CXL was significantly correlated with changes in keratometry values, with total corneal RMS-HOAs, vertical coma, and vertical trefoil, and with corneal epithelial RMS-HOAs (all p<0.05). Conclusion: Besides total corneal aberrations, corneal epithelial aberrations may also influence the improvement of visual acuity and quality after A-CXL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.