Evidence map›Paper›PMID 42037256›Full record

ArticleBiochemistry2026

Multiscale Modeling of the Bacterial Ribosome to Identify Potential Peptide Modulators and Their Allosteric Effects.

Merve Yuce, Fethiye Aylin Sungur, Ozge Kurkcuoglu

Abstract read
In one paragraph

Article in Biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Merve YuceDepartment of Chemical Engineering, Istanbul Technical University, Istanbul 34469, Turkey.ORCID 0000-0003-3257-1097
Fethiye Aylin SungurComputational Science and Engineering Division, Informatics Institute, Istanbul Technical University, Istanbul 34469, Turkey.ORCID 0000-0003-3245-742X
Ozge KurkcuogluDepartment of Chemical Engineering, Istanbul Technical University, Istanbul 34469, Turkey.ORCID 0000-0003-0228-3211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bacterial ribosome is a key antibiotic target, yet peptide-based modulation from its functional and allosteric sites is underexplored. We developed a computational pipeline combining SiteMap-derived binding-site detection, consensus docking with Glide and rDock, all-atom truncated molecular dynamics (MD), and coarse-grained MD (CGMD) simulations to identify peptide candidates against four

Indexed as

Escherichia coliPeptidesRibosomesAllosteric RegulationAllosteric SiteBinding SitesMolecular Dynamics SimulationPeptides

Identifiers

PMID42037256
PMCPMC13348021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.