ArticleNucleic acids research2026
HMMER web server: 2026 update.
Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- A Natural qE- and qZ-Deficient Alga Retains Functional Plant-Like and Chlorophycean Violaxanthin De-Epoxidases.bioRxiv : the preprint server for biology · 2026Article
- Functional redundancy driven by isocitrate dehydrogenase enhances metabolic robustness in Pseudomonas putida KT2440.Microbial cell factories · 2026Article
- Genomic and Phenotypic Characterization of Avian-DerivedAnimals : an open access journal from MDPI · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The HMMER web server, available at https://www.ebi.ac.uk/Tools/hmmer, provides online access to tools from the HMMER software suite (http://hmmer.org/) for protein analysis using profile hidden Markov models. Users can perform sequence similarity searches against a range of regularly updated protein sequence databases or annotate protein sequences with domains and families using profile HMM libraries from protein family databases. Since the 2018 update, the continued exponential growth of sequence databases has necessitated substantial infrastructural improvements to maintain search performance speed and service reliability. To achieve this, the web interface has been completely reengineered using modern web technologies (JavaScript and React), providing users with an enhanced experience, including session-based search history and streamlined results visualization. The web application programming interface has been rewritten to better support programmatic access with updated endpoints and JSON-based responses. The infrastructure has been redesigned to efficiently handle searches against much larger databases through horizontal scaling and asynchronous job processing. Target database offerings have been updated to reflect current usage patterns and data availability. The HMMER web server is free and open to all users, and there is no login requirement.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.