Evidence map›Paper›PMID 42037095›Full record

ArticleVeterinary and comparative oncology2026

Prognostic Significance of the Tumour Microenvironment in Surgically Resected Canine Pulmonary Adenocarcinomas.

Masanao Ichimata, Yumiko Kagawa, Atsushi Toshima, Fukiko Matsuyama, Eri Fukazawa, Kei Harada, Ryuzo Katayama, Yuko Nakano, Tetsuya Kobayashi, Masaya Igase and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary and comparative oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Masanao IchimataLaboratory of Molecular Diagnostics and Therapeutics, Joint Graduate School of Veterinary Medicine, Yamaguchi University, Yamaguchi, Yamaguchi, Japan.ORCID https://orcid.org/0000-0003-0925-0981
Yumiko KagawaNorth Lab, Sapporo, Hokkaido, Japan.ORCID https://orcid.org/0009-0006-0078-1443
Atsushi ToshimaPublic Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0009-0000-5190-6396
Fukiko MatsuyamaJapan Small Animal Cancer Center, Public Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-1021-7735
Eri FukazawaJapan Small Animal Cancer Center, Public Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0009-0003-6435-529X
Kei HaradaJapan Small Animal Cancer Center, Public Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-3345-9200
Ryuzo KatayamaJapan Small Animal Cancer Center, Public Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0009-0006-0757-3751
Yuko NakanoJapan Small Animal Cancer Center, Public Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0009-0009-5148-8281
Tetsuya KobayashiJapan Small Animal Cancer Center, Public Interest Incorporated Foundation Japan Small Animal Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-0100-8579
Masaya IgaseLaboratory of Molecular Diagnostics and Therapeutics, Joint Graduate School of Veterinary Medicine, Yamaguchi University, Yamaguchi, Yamaguchi, Japan.ORCID https://orcid.org/0000-0002-3118-8507
Takuya MizunoLaboratory of Molecular Diagnostics and Therapeutics, Joint Graduate School of Veterinary Medicine, Yamaguchi University, Yamaguchi, Yamaguchi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognostic relevance of the tumour microenvironment in surgically resected canine pulmonary adenocarcinomas (cPACs) remains uncertain. This retrospective single-centre cohort study evaluated associations between intratumoural immune features and postoperative outcomes. Dogs treated between 2005 and 2021 with histologically confirmed cPACs that had undergone surgical excision and had an evaluable tumour microenvironment were included. Immunohistochemistry for CD8, Foxp3, CD3 and CD20 was performed. CD8+ and Foxp3+ cell densities were quantified in five intratumoural hotspots of 0.237 mm

Indexed as

AdenocarcinomaDog DiseasesLung NeoplasmsTumor MicroenvironmentAnimalsDogsFemaleMalePrognosisRetrospective Studiescanine pulmonary adenocarcinomaCD20+ B cellsCD8+ T cellslymphoid aggregatesregulatory T cellstertiary lymphoid structurestumour‐infiltrating lymphocytes

Identifiers

PMID42037095
PMCPMC13456590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.