Evidence map›Paper›PMID 42037051›Full record

ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2026

Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology.

Mariana Valdez Aguilar, Gabriela K Giulumian, Isabel Rodriguez, Jessica H Baker, Preina P Surti, Lisa Dinkler, Jerry Guintivano, Jessica S Johnson, Casey M MacDermod, Shelby N Ortiz and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in European eating disorders review : the journal of the Eating Disorders Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05605067 (Genetic Architecture of Avoidant/Restrictive Food Intake Disorder), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05605067 completednot on this map

Genetic Architecture of Avoidant/Restrictive Food Intake Disorder

TypeobservationalSponsorUniversity of North Carolina, Chapel HillRan2023 to 2024Enrolled5,076ConditionsARFID, Eating Disorders, Eating Disorders in Children, Eating, Picky
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mariana Valdez AguilarDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Gabriela K GiulumianDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Isabel RodriguezDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jessica H BakerDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-3997-2398
Preina P SurtiDepartment of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lisa DinklerDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Jerry GuintivanoDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jessica S JohnsonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Casey M MacDermodDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Shelby N OrtizDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0001-8088-8254
Emily M PisetskyDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jennifer P WhiteDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Nadia MicaliCenter for Eating and Feeding Disorders Research, Mental Health Center Ballerup, Copenhagen University Hospital-Mental Health Services CPH, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-5571-2273
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0001-7772-3264
Laura M ThorntonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0001-9384-7988
Ya-Ke WuDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0001-8990-3449

Funding

Genetic Architecture of Avoidant/Restrictive Food Intake DisorderR56MH129437 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, MICALI, NADIA · 2022 to 2023
$1.5M
NIMH NIH HHS R56MH129437Office of Community Development
6 · The paper itself

Abstract

objectiveAlthough obsessive-compulsive disorder (OCD) commonly co-occurs with anorexia nervosa and bulimia nervosa, less is known about its relationship with avoidant/restrictive food intake disorder (ARFID) dimensions. Whether associations between ARFID dimensions and OCD differ by sex is also unclear. We examined associations between ARFID dimensions and OCD symptoms by sex, accounting for depression and anxiety.

methodsData from 3120 participants ages 15+ in the ARFID Genes and Environment (ARFID-GEN) study were analyzed. ARFID dimensions (i.e., sensory sensitivity; low appetite/lack of interest in food; and fear of aversive consequences), OCD symptoms, anxiety, and depression were assessed using validated self-report measures. We evaluated associations between ARFID dimensions and OCD symptoms using general linear models, adjusting for depression and anxiety.

resultsARFID dimensions were significantly associated with OCD symptoms. After adjusting for depression and anxiety, these associations were attenuated but remained significant for all ARFID dimensions. Associations between ARFID dimensions and OCD symptoms varied by sex.

conclusionThe relation between ARFID symptomatology and OCD warrants further exploration across the developmental spectrum in which ARFID appears. Clinically, bidirectional screening may improve diagnostic clarity and be informative to tailor interventions appropriately.

trial registrationARFID-GEN is registered in clinicaltrials.gov (NCT05605067).

Indexed as

Avoidant Restrictive Food Intake DisorderObsessive-Compulsive DisorderAdolescentAdultAnxietyDepressionFemaleHumansMaleMiddle AgedYoung Adultanxietydepressioneating disordersfeeding disordersobsessive‐compulsive symptomatology

Identifiers

PMID42037051
PMCPMC13432419

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.