Evidence map›Paper›PMID 42036788›Full record

ArticleMagnetic resonance in medicine2026

Faster and More Robust CK Reaction Rate Estimation at 3T Using Acquisition-Weighted

Aaron Axford, Iveta Pajanová, William D Watson, Andrew C Tyler, Roshan Xavier, Ferenc E Mózes, Oliver J Rider, Damian J Tyler, Ladislav Valkovič

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aaron AxfordOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0009-0007-5954-8977
Iveta PajanováOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.
William D WatsonOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.
Andrew C TylerOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.
Roshan XavierOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.
Ferenc E MózesOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-1361-4349
Oliver J RiderOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.
Damian J TylerOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.
Ladislav ValkovičOxford Centre for Clinical MR Research (OCMR), RDM Cardiovascular Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0003-2567-3642

Funding

British Heart Foundation FS/19/18/34252British Heart Foundation FS/SCRF/22/32014EU NextGenerationEU through the Recovery and Resilience Plan for Slovakia 09I03-03-V02-00016Oxford-Bristol Myers Squibb FellowshipSlovak Research and Development Agency 21-0299Vedecká grantová agentúra MŠVVaM SR a SAV (VEGA) 2/0084/26Wellcome Trust 221805/Z/20/Z
6 · The paper itself

Abstract

purposeQuantification of the creatine kinase (CK) forward reaction rate (k

methodsHealthy volunteers were scanned with a fully weighted (FW) TRiST protocol twice, and once with an AW TRiST protocol on a 3T MRI. The resulting spectra were reconstructed with conventional Fourier Transform (FT), as well as compartment-based reconstruction techniques: Spectroscopy with Linear Algebra Modeling (SLAM), Spectral Localization by IMaging (SLIM), and an unweighted mean of the FT spectra (ROI-FT). k

resultsThe cardiac k

conclusionCompartment-based reconstruction techniques minimize the operator subjectivity present in the current FT method of analyzing TRiST experiments, in addition to reducing skeletal muscle contamination. When combined with an AW acquisition, scan times were reduced by 47% without compromising k

Indexed as

Creatine KinaseImage Processing, Computer-AssistedMagnetic Resonance ImagingMyocardiumAdultAlgorithmsFemaleFourier AnalysisHeartHumansMagnetic Resonance SpectroscopyMalePhosphorus IsotopesReproducibility of ResultsSensitivity and SpecificityCreatine KinasePhosphorus Isotopes

Identifiers

PMID42036788
PMCPMC13327432

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.