Evidence map›Paper›PMID 42036649›Full record

ArticleBMC musculoskeletal disorders2026

Clinical effects and prognostic factors of combined laminoplasty with keyhole decompression for multilevel cervical spondylotic myelopathy: analysis based on cervical sagittal parameters.

Huajie Gu, Liyong Shang, Weifeng Ling, Weiyu Jiang

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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Huajie GuYangming Hospital Affiliated to Ningbo University (Yuyao People 's Hospital), Orthopaedics, Yuyao, Zhejiang, 315400, China.
Liyong ShangYangming Hospital Affiliated to Ningbo University (Yuyao People 's Hospital), Orthopaedics, Yuyao, Zhejiang, 315400, China.
Weifeng LingYangming Hospital Affiliated to Ningbo University (Yuyao People 's Hospital), Orthopaedics, Yuyao, Zhejiang, 315400, China.
Weiyu JiangDepartment of Spinal Surgery, Ningbo Sixth Hospital, Ningbo, Zhejiang, 315000, China. lllwww1128@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExpansive open-door laminoplasty is standard for multilevel cervical spondylotic myelopathy (MCSM), but suboptimal for concurrent radiculopathy. The clinical value of additional keyhole decompression and its impact on cervical sagittal alignment remain unclear.

objectiveWe hypothesized that combined laminoplasty with keyhole decompression would provide superior radicular symptom relief compared to laminoplasty alone in MCSM patients with varying radicular severity, while maintaining sagittal alignment, with surgical technique, disease duration, and nerve root compression severity as independent prognostic factors. This study evaluates clinical outcomes, sagittal parameters, and prognostic factors.

methodsRetrospective analysis of 94 MCSM patients (January 2021-December 2022): 34 combined group, 60 laminoplasty group. Outcomes (JOA, NDI, VAS) and sagittal parameters assessed preoperatively, 1-month, and 1-year postoperatively. Propensity score matching (PSM) addressed selection bias; multivariate regression identified predictors.

resultsJOA improvement rates comparable (combined: 47.8 ± 12.4% vs. laminoplasty: 46.2 ± 11.8%, P > 0.05). Combined group showed superior NDI (15.2 ± 5.4% vs. 18.6 ± 5.8%, P = 0.008, Cohen’s d = 0.61) and VAS (1.0 ± 0.6 vs. 2.2 ± 0.8, P < 0.001, d = 1.68) improvements. Post-PSM results consistent. Sagittal changes (decreased C2-C7 Cobb, increased cSVA/T1 slope, P < 0.05) similar between groups. Predictors: surgical technique (β = 0.386, P = 0.008), disease duration (β=-0.312, P = 0.006), compression severity (β = 0.368, P = 0.010; GRADE: moderate-high evidence).

conclusionsCombined approach offers superior radicular relief without compromising alignment or neurological recovery. Evidence-based patient stratification and prognostic modeling advance personalized MCSM management; future RCTs needed to validate.

Indexed as

Cervical VertebraeDecompression, SurgicalLaminoplastyRadiculopathySpinal Cord DiseasesSpondylosisAgedFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesTreatment OutcomeCervical sagittal balanceExpansive laminoplastyKeyhole foraminotomyMultilevel cervical spondylotic myelopathyPrognostic factorsSurgical outcome

Identifiers

PMID42036649
PMCPMC13251234

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.