Evidence map›Paper›PMID 42036588›Full record

ArticleCalcified tissue international2026

Mechanosensitive Piezo1 Channels in Enamel Cells.

Guilherme H Souza Bomfim, Anna Zou, Fabio A Echeverry, Ai Thu Bui, Edisa de Oliveira Sousa, Bruno Luis Graciliano Silva, Lukasz Witek, William A Coetzee, Rodrigo S Lacruz

Abstract read
PubMed Publisher
In one paragraph

Article in Calcified tissue international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Editorial "Enamel" Issue.Calcified tissue international · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guilherme H Souza BomfimDepartment of Molecular Pathobiology, Metabolism & Inflammation Research Group, New York University College of Dentistry, New York, NY, 10010, USA.
Anna ZouDepartment of Molecular Pathobiology, Metabolism & Inflammation Research Group, New York University College of Dentistry, New York, NY, 10010, USA.
Fabio A EcheverryDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, 10016, USA.
Ai Thu BuiDepartment of Oral and Craniofacial Sciences, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Edisa de Oliveira SousaBiomaterials and Regenerative Biology Division, Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, 10010, USA.
Bruno Luis Graciliano SilvaBiomaterials and Regenerative Biology Division, Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, 10010, USA.
Lukasz WitekBiomaterials and Regenerative Biology Division, Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, 10010, USA.
William A CoetzeeDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, 10016, USA.
Rodrigo S LacruzDepartment of Molecular Pathobiology, Metabolism & Inflammation Research Group, New York University College of Dentistry, New York, NY, 10010, USA. rsl10@nyu.edu.

Funding

New York University MA003NIDCR NIH HHS DE027679
6 · The paper itself

Abstract

Ameloblasts are specialized epithelial cells that form enamel during the secretory and maturation stages, the latter involving an increase in Ca

Indexed as

AmeloblastsDental EnamelIon ChannelsMechanotransduction, CellularAnimalsCalciumCells, CulturedMiceRatsCalciumIon ChannelsPiezo1 protein, ratAmeloblasts, Piezo1Ca2+ signalingIon channelsMechanosensitive channels

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.