Evidence map›Paper›PMID 42036574›Full record

ReviewAdvances in experimental medicine and biology2026

Insights into Dysregulated GABAergic Synapses and Depression: A Complex and Evolving Relationship.

Ayla Arslan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ayla ArslanÜsküdar University, Faculty of Engineering and Natural Sciences, Department of Molecular Biology and Genetics, Istanbul, Türkiye. ayla.arslan@uskudar.edu.tr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The γ-aminobutyric acid (GABA) system, as the primary inhibitory network in the mammalian brain, plays a central role in the pathophysiology of numerous neurological and psychiatric conditions. At the core of this system are GABAergic synapses, which are composed of a complex array of organizational, functional, and modulatory proteins. Despite their fundamental importance, the molecular diversity and organization of GABAergic synapses remain only partially understood. This chapter highlights relatively well-characterized molecular components of GABAergic synapses, with particular emphasis on depression pathophysiology.

Indexed as

DepressionGABAergic Neuronsgamma-Aminobutyric AcidSynapsesAnimalsAntidepressive AgentsHumansReceptors, GABA-ASynaptic TransmissionAntidepressive Agentsgamma-Aminobutyric AcidReceptors, GABA-AAntidepressantBenzodiazepinesDepressionGABAGABAA receptorsGephyrinGWASInhibitory synapseNeuroactive steroidsNeuroligin-2StressSynapse

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.