Evidence map›Paper›PMID 42036418›Full record

ArticleScientific reports2026

Usefulness of the Stroop test in predicting decompensation events in patients with cirrhosis: A prospective cohort study.

Masashi Aiba, Takao Miwa, Sachiyo Hirata, Satomi Nakashima, Kayoko Nishimura, Mikita Oi, Shinji Unome, Kenji Imai, Koji Takai, Masahito Shimizu

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Masashi AibaDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Takao MiwaDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan. miwa.takao.a6@f.gifu-u.ac.jp.
Sachiyo HirataCenter for Nutrition Support and Infection Control, Gifu University Hospital, 1-1 Yanagido, Gify, 501-1194, Japan.
Satomi NakashimaCenter for Nutrition Support and Infection Control, Gifu University Hospital, 1-1 Yanagido, Gify, 501-1194, Japan.
Kayoko NishimuraCenter for Nutrition Support and Infection Control, Gifu University Hospital, 1-1 Yanagido, Gify, 501-1194, Japan.
Mikita OiDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Shinji UnomeDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Kenji ImaiDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Koji TakaiDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Masahito ShimizuDepartment of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Stroop test is used at the point of care to identify covert hepatic encephalopathy (CHE). However, it is unclear whether performance on the Stroop test can predict decompensation in patients with cirrhosis. This prospective cohort study included patients with cirrhosis admitted to the Gifu University Hospital in Japan. CHE was assessed using the Stroop test reference value determined by the Japan Society of Hepatology. Decompensation was defined as the onset of overt hepatic encephalopathy (OHE), bacterial infection, gastrointestinal bleeding, or esophageal varices. The factors associated with decompensation were assessed using the Fine–Gray competing risk regression model. Of 290 patients, CHE was present in 25 (8.6%). During a median follow-up period of 2.4 years, decompensation events occurred in 99 (34.1%) patients, including 51 (17.6%) bacterial infections, 49 (16.9%) cases of OHE, and 23 (7.9%) episodes of gastrointestinal bleeding or esophageal varices. The incidence of decompensation was significantly higher in patients with CHE than in those without (60.0% vs. 31.7%; p < 0.001). Multivariable analysis revealed that CHE (sub-distribution hazard ratio [SHR], 1.89; 95% confidence interval [CI], 1.09–3.28) was an independent predictor of decompensation events. CHE was also a significant factor for OHE (SHR, 3.47; 95% CI, 1.73–6.98) and bacterial infection (SHR, 2.57; 95% CI, 1.14–5.77). The Stroop test can predict decompensation events and stratify the risks of OHE and bacterial infections in patients with cirrhosis.

Indexed as

Hepatic EncephalopathyLiver CirrhosisStroop TestAgedBacterial InfectionsEsophageal and Gastric VaricesFemaleGastrointestinal HemorrhageHumansJapanMaleMiddle AgedProspective StudiesRisk FactorsBacterial infectionCovert hepatic encephalopathyHepatic encephalopathyMinimal hepatic encephalopathyNeuropsychological testOvert hepatic encephalopathy

Identifiers

PMID42036418
PMCPMC13284250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.