Evidence map›Paper›PMID 42035465›Full record

SynthesisClinical and experimental dental research2026

Association Between Obstructive Sleep Apnea and Periodontitis: A Systematic Umbrella Review.

Mohammed Khalid Mahmood, Shahen Hiwa Omer, Sarhang Sarwat Gul, Yad Mariwan Mohammed Amin, Herve Tassery, Delphine Tardivo, Romain Lan

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical and experimental dental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammed Khalid MahmoodCollege of Dentistry, Sulaymaniyah University, Sulaymaniyah, Iraq.ORCID 0000-0002-8093-9514
Shahen Hiwa OmerDepartment of Dentistry, Komar University of Science and Technology, Sulaymaniyah, Iraq.
Sarhang Sarwat GulMedical Laboratory Department, College of Health and Medical Technology, Sulaymaniyah Polytechnic University, Sulaymaniyah, Iraq.ORCID 0000-0003-1413-4934
Yad Mariwan Mohammed AminDepartment of Dentistry, Tishk International University, Sulaymaniyah, Iraq.
Herve TasseryDental School of Medicine, Conservative and Endodontic Department, Aix-Marseille University, Marseille, France.
Delphine TardivoFaculty of Medical and Paramedical Sciences, French National Center of Scientific Research (CNRS), French Blood Establishment (EFS), Bio-Cultural Anthropology, Law, Ethics and Health Laboratory (ADES), Aix-Marseille University, Marseille, France.
Romain LanFaculty of Medical and Paramedical Sciences, French National Center of Scientific Research (CNRS), French Blood Establishment (EFS), Bio-Cultural Anthropology, Law, Ethics and Health Laboratory (ADES), Aix-Marseille University, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to evaluate the association between obstructive sleep apnea (OSA) and periodontitis using an umbrella meta-analysis (MA).

methodsPubMed, MEDLINE, Web of Science, Scopus, Embase, and Google Scholar databases were systematically searched before December 2025. MAs reporting odds ratios (OR) for the association between OSA and periodontitis were included. Methodological quality was assessed using AMSTAR-2, and certainty of evidence was evaluated using GRADE. Random-effects MA was performed. Egger's test and trim-and-fill analysis were used to assess the publication bias.

resultsSeven MAs encompassing over 225,000 participants were included. A significant association was found between OSA and periodontitis (OR 1.96, 95% CI 1.68-2.29, p < 0.0001), with substantial heterogeneity (I

conclusionsThe results of this review suggest a significant association between OSA and periodontitis, with a greater association of severe OSA with periodontitis. Future studies should examine the impact of periodontal therapy on OSA severity and vice versa. PROSPERO REGISTRATION: CRD420251241137.

Indexed as

PeriodontitisSleep Apnea, ObstructiveHumansRisk Factorsmeta‐analysisobstructive sleep apneaperiodontitissleep disorderssystematic review

Identifiers

PMID42035465
PMCPMC13110838

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.