Evidence map›Paper›PMID 42035460›Full record

ArticleClinical and experimental dental research2026

Effect of Suturing and Adhesive Fixation on Free Gingival Graft Stability: An Ex-Vivo Porcine-Model Study.

Kevimy Agossa, Khushboo Kalani, Parham Hazrati, Chi-Fan Chen, Chen-Lin Tsai, Dumitru Chele, Abdusalam E Alrmali, Hom-Lay Wang

Abstract read
In one paragraph

Article in Clinical and experimental dental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevimy AgossaDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0003-4305-1353
Khushboo KalaniDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0009-0008-3842-6150
Parham HazratiDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0002-8362-3208
Chi-Fan ChenDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0009-0000-2025-521X
Chen-Lin TsaiDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0009-0007-9438-3784
Dumitru CheleDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0003-2231-8741
Abdusalam E AlrmaliDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0001-7437-6279
Hom-Lay WangDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.ORCID 0000-0003-4238-1799

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesClinician expertise influences approach choices, amidst ongoing research on suturing techniques' biomechanical effects on graft stability. This study evaluated different suturing methods and cyanoacrylate adhesive for FGG fixation with a porcine mandible model. MATERIAL AND

methodsNinety-four FGG procedures were performed on juvenile pig mandibles. Eight fixation methods were evaluated: seven suturing techniques-Cross Compression (CC), Vertical Circumferential Compression (VCC), Horizontal (H), CC + H, VCC + H, Miller (MIL), Holbrook and Ochsenbein (Chan et al.)-and cyanoacrylate adhesive (GLU). Outcomes measured included marginal tension (vertical displacement force) and lateral tension (horizontal displacement) at the graft margin.

resultsThe HOC technique demonstrated the highest marginal stability (3.82 (SD 1.35 N) and compressive resistance (0.76 (SD 0.48 N). CC + H and VCC + H also showed significantly enhanced marginal stability. Compared to MIL, HOC exhibited superior compressive resistance (p = 0.001), while both HOC and CC + H achieved significantly greater marginal tension (p < 0.05). Graft dimensions influenced outcomes: greater graft height improved compressive resistance, while increased length reduced marginal stability with horizontal sutures. Mean suturing time was 4.84 min (SD 1.55); CC was faster than MIL (p = 0.03), whereas HOC, CC + H, and VCC + H required significantly more time (p < 0.01). GLU achieved marginal stability (3.45 (SD 3.2 N) comparable to HOC.

conclusionsWithin the limitations of this ex vivo study, suturing technique and graft dimensions significantly affect the FGG's biomechanical stability. Holbrook and Ochsenbein's suturing technique achieved the highest marginal stability and compressive resistance. Furthermore, tissue adhesive demonstrated comparable performance to conventional sutures, supporting its potential as an alternative fixation method.

Indexed as

GingivaSuture TechniquesTissue AdhesivesAnimalsBiomechanical PhenomenaCyanoacrylatesMandibleModels, AnimalSwineCyanoacrylatesTissue Adhesivesanimalautograftmodelssuturesswinetissue adhesives

Identifiers

PMID42035460
PMCPMC13110839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.