ArticleAmerican journal of industrial medicine2026
Serum PFAS in Aircraft Rescue and Firefighting (ARFF) Firefighters From Six U.S. Airport Fire Departments.
Article in American journal of industrial medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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20 authors.
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Abstract
introductionUse of aqueous film-forming foam (AFFF) is a source of exposure to per- and polyfluoroalkyl substances (PFAS) for firefighters working in aircraft rescue and firefighting (ARFF) settings. However, data characterizing the association between serum PFAS concentrations and exposure risk factors for ARFF firefighters are limited.
methodsIn this cross-sectional study, ARFF firefighters (N = 193) from six U.S. commercial airports provided serum for quantification of nine PFAS and completed a survey in 2019-2020. A drinking water sample from each fire station was also analyzed for 29 PFAS. Serum PFAS concentrations were compared with demographically-similar participants from the National Health and Nutrition Examination Survey (NHANES) 2017-March 2020. Multivariable linear regression was used to identify factors associated with serum PFAS concentrations.
resultsGeometric mean serum concentrations of perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS) branched isomers, and perfluoroundecanoic acid (PFUnDA) were statistically higher in ARFF firefighters compared with NHANES participants. PFAS were detected in tap water at three fire departments, but only one department was characterized by detection of select PFAS (perfluorooctanoic acid (PFOA), PFOS, and PFHxS) in both water and serum. Past employment, detection of PFAS in drinking water, and age were positively associated with select PFAS concentrations; a recent change in workplace AFFF behavior or practice, female sex, and Black race exhibited inverse associations.
conclusionsParticipants reporting changes in workplace behavior, policy, or practice had lower summed PFAS concentrations, suggesting these measures may help reduce exposure. Continued research is needed to evaluate exposure reduction strategies for firefighters, particularly those working in ARFF settings.
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