ArticleInflammatory bowel diseases2026
Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study.
Article in Inflammatory bowel diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe association between inflammatory bowel disease (IBD) without active perineal disease and the risk of perineal trauma during vaginal birth remains unclear. Thus, we aimed to determine whether IBD without active perianal disease is independently associated with perineal trauma.
methodsA retrospective cohort study including all primiparous women with singleton, cephalic, term pregnancies who delivered vaginally at a tertiary medical center between 2012 and 2023. Women with IBD without active perianal disease were compared with women without IBD. Women with active perianal disease were excluded according to institutional guidelines. The primary outcomes included overall perineal injury, defined as any spontaneous perineal tear, labial laceration, obstetric anal sphincter injury (OASI), and episiotomy. Multivariable logistic regression was performed to assess the association between inflammatory bowel disease and perineal trauma, adjusting for potential confounders.
resultsAmong 45,250 primiparous women, 244 women (0.5%) had IBD. Overall perineal injury rates were similar between the IBD and control groups (84.0% vs. 85.4%; P = .553). OASI was comparable (0.4% vs. 0.9%; P = .728), and episiotomy rates did not differ significantly. In multivariable analysis, IBD was not associated with perineal trauma (aOR 0.82; 95% CI 0.56-1.19, P = .288). Independent predictors included vacuum-assisted delivery, higher birthweight, occiput posterior presentation, prolonged second stage, and epidural analgesia. Subgroup analysis showed no differences between ulcerative colitis and Crohn's disease.
conclusionIBD without active perianal disease does not increase the risk of perineal injury in primiparous women undergoing term vaginal delivery. Vaginal birth is an appropriate mode of delivery in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.