Evidence map›Paper›PMID 42035290›Full record

ArticleScience progress

Association between age-adjusted visceral fat index (AVAI) and congestive heart failure: A cross-sectional study.

Guohao Li, Xiaoying Li, Junyuan Situ, Daojin Gan, Qiming Zhao, Xiao Wang, Tianming Lai, Dingli Xu

Abstract read
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Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Guohao LiState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0009-0002-4216-8373
Xiaoying LiDepartment of Cardiology, Foshan Sanshui District People's Hospital, Foshan, China.
Junyuan SituState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Daojin GanState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Qiming ZhaoState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiao WangState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Tianming LaiState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Dingli XuState Key Laboratory of Organ Failure Research, Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID 0000-0002-3193-4354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveCongestive heart failure (CHF) is a chronic disease marked by impaired cardiac function, and excess visceral fat has been reported to be associated with CHF. While the age-adjusted visceral adiposity index (AVAI) is a novel metric for evaluating visceral fat, its association with CHF has not been well elucidated.MethodsThe association between AVAI and CHF prevalence was assessed using cross-sectional data from the 2013-2018 National Health and Nutrition Examination Survey (NHANES). Logistic regression was used to assess the association between AVAI and CHF prevalence, with sequential adjustment for covariates. Subgroup analyses stratified by demographic variables and lifestyle factors were done to examine the robustness of the results. Lastly, the discriminative ability of VAI and AVAI in distinguishing individuals with and without prevalent CHF was evaluated using receiver operating characteristic (ROC) curve analysis.ResultsA total of 6,695 participants were included in the analysis, comprising 6,470 without CHF and 225 with CHF. Logistic regression revealed a significant positive association between AVAI and CHF prevalence (OR = 1.75, 95% CI: 1.62-2.89), which remained robust after adjusting for confounders (adjusted OR = 1.57, 95% CI: 1.31-1.87). In subgroup studies, AVAI was consistently associated with the prevalence of CHF. ROC analysis indicated that AVAI demonstrated superior discriminative performance compared with VAI in distinguishing individuals with and without prevalent CHF.ConclusionsThis cross-sectional study identified a significant association between AVAI and prevalent CHF. AVAI may represent a clinically relevant marker associated with the prevalence of CHF and may help identify populations with a higher likelihood of prevalent CHF for further prospective investigation.

Indexed as

Heart FailureIntra-Abdominal FatAdultAgedAge FactorsCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsROC Curveage-adjusted visceral adiposity indexcongestive heart failureNHANESobesityvisceral adiposity index

Identifiers

PMID42035290
PMCPMC13129316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.