Evidence map›Paper›PMID 42035279›Full record

ArticleAutophagy2026

AutoDRY: a genome-wide resource revealing phase-specific control of autophagy activation, amplitude, and termination.

Jorrit M Enserink, Nathalia Chica

Abstract read
In one paragraph

Article in Autophagy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jorrit M EnserinkDepartment of Molecular Cell Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.ORCID 0000-0002-2394-5387
Nathalia ChicaDepartment of Molecular Cell Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, Norway.ORCID 0000-0002-1068-2549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite decades of research identifying the core autophagy-related (ATG) gene products that execute macroautophagy (hereafter autophagy), a systems-level understanding of how the broader genome dynamically tunes this process remains limited. Most studies rely on bulk assays that capture cumulative degradation at a single time point, making it difficult to resolve how autophagy is activated, sustained, and terminated over time. In addition, approaches to quantify temporal response kinetics across thousands of genotypes in parallel at the population level have been lacking, hindering predictive modeling and the development of precise pharmacological strategies to modulate autophagy.

Indexed as

AutophagyGenomeAnimalsHumansSaccharomyces cerevisiaeAutophagy dynamicsautophagy terminationbioinformaticssystems biologyyeast

Identifiers

PMID42035279
PMCPMC13449838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.