Evidence map›Paper›PMID 42035278›Full record

ArticleAutophagy2026

Overexpression of autophagy genes activates lipophagy in Arabidopsis.

Jilian Fan, Saroj Kumar Sah, Dongling Xie, Changcheng Xu

Abstract read
In one paragraph

Article in Autophagy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jilian FanBiology Department, Brookhaven National Laboratory, Upton, NY, USA.
Saroj Kumar SahBiology Department, Brookhaven National Laboratory, Upton, NY, USA.
Dongling XieBiology Department, Brookhaven National Laboratory, Upton, NY, USA.
Changcheng XuBiology Department, Brookhaven National Laboratory, Upton, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells possess an intrinsic recycling system called macroautophagy/autophagy, which delivers obsolete or damaged cytoplasmic components into the vacuole for degradation and reuse. Autophagy-mediated breakdown of organellar membrane lipids supplies fatty acids for the synthesis of triacylglycerols (TAGs), which are then packaged into subcellular organelles called lipid droplets (LDs). Conversely, autophagy contributes to TAG turnover by delivering LDs into vacuoles for breakdown by resident acid lipases. Additionally, LDs can undergo degradation through cytosolic lipolysis mediated by SDP1 (Sugar-Dependent1) lipase in Arabidopsis. Autophagy-mediated LD, a process referred to as lipophagy, has been described in plants. Nevertheless, the precise mechanisms of lipophagy and the specific types of vacuoles involved remain unclear. Here, we show that overexpression of autophagy genes

Indexed as

ArabidopsisAutophagyArabidopsis ProteinsAutophagy-Related Protein 5Autophagy-Related Protein 8 FamilyCarboxylic Ester HydrolasesGene Expression Regulation, PlantLipid DropletsTriglyceridesVacuolesArabidopsis ProteinsAtg5 protein, ArabidopsisATG8 protein, ArabidopsisAutophagy-Related Protein 5Autophagy-Related Protein 8 FamilyCarboxylic Ester HydrolasesSDP1 protein, ArabidopsisTriglyceridesArabidopsis thalianaATG5ATG8autophagic vacuolelipid dropletlipophagy

Identifiers

PMID42035278
PMCPMC13557581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.