ArticleThe Laryngoscope2026
Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing.
Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Validation of the TruBlue Light Laser for Laryngeal Somatosensory and Perturbation Testing.The Laryngoscope · 2026Article
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7 authors.
Funding
Abstract
objectivesClinical assessment of laryngeal somatosensation is limited by the lack of precise tools to directly stimulate the larynx and quantify sensorimotor responses. This study validated a blue light laser method for laryngeal somatosensory testing in vocally healthy adults and developed acoustic measures to quantify vocal responses to controlled laryngeal perturbations.
methodsIn this prospective validation study, a 445-nm diode blue light laser was delivered through a channeled flexible laryngoscope to the arytenoid mucosa. Single subablative pulses (1-10 W, 30 ms) were applied during quiet breathing or sustained phonation to determine perceptual and reflexive sensory thresholds, discrimination acuity, and laryngeal perturbation responses. Acoustic recordings during perturbations were analyzed in Praat using custom software to extract continuous fundamental frequency variability and quantify perturbation magnitude and recovery.
resultsParticipants demonstrated reliable perceptual detection and laryngeal reflexive responses to laser stimulation. Mean perceptual sensory threshold was 1.46 W (SD = 1.17) and mean laryngeal response threshold was 4.62 W (SD = 2.04). Sensory ratings were higher during stimulation than foil trials (p < 0.001). Sensory perception increased with stimulation intensity (~0.3 points per 1 W; p < 0.001), and higher wattage increased odds of eliciting a laryngeal response (OR = 1.38; p < 0.001). Discrimination accuracy averaged 78.5% (OR = 1.45; p = 0.002). Laser stimulation during phonation produced measurable acoustic perturbations (peak SD(f
conclusionBlue light laser stimulation is a feasible and precise method for evaluating laryngeal somatosensation and vocal sensorimotor responses. LEVEL OF EVIDENCE: 3:
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