ArticleAntimicrobial resistance and infection control2026
Genomic investigation of the vancomycin-resistant Enterococcus faecium in a tertiary hospital in China.
Article in Antimicrobial resistance and infection control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesIn light of a VREfm spread in a large tertiary hospital in China, this study aimed to explore the transmission dynamics and genetic characteristics of these isolates within a global context.
methodsA total of 27 VREfm were collected from a hospital in Guangdong province, China. Antimicrobial susceptibility testing, whole-genome sequencing, and transmission dynamics analysis were performed. Additionally, global sequence type 80 (ST80) data were gathered for genetic comparison, and complete plasmid sequences were reconstructed to characterize the genetic environment surrounding the vanA genes.
resultsThe study identified VREfm ST80 as the main agent of the patient infection, with the exception of four ST789 isolates identified on environmental surfaces within one bed. The genomes displayed high clustering, with similar profiles of virulence factors and antimicrobial resistance genes. The study observed that genetically similar VREfm strains were distributed across different beds. Moreover, VREfm ST80 from the hospital clustered with other Chinese isolates and exhibited a higher number of VFs compared to other lineages. Although vanA genes were present in different STs, the vanA-carrying plasmids shared highly similar backbone structure, with Tn1546-associated elements detected in each.
conclusionThis study sheds light on the genetic epidemiology of a VREfm spread in a Chinese hospital through comparison with global isolates. To control the spread of VREfm within hospitals, the implementation of active screening programs and rigorous infection control measures is essential.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.