Evidence map›Paper›PMID 42035149›Full record

ArticleTrials2026

Effect of constraint standing training on balance and gait in hemiparetic stroke patients: a single-blind randomized controlled trial protocol.

Liping Zhou, Huaide Chu, Manting Cao, Nur Arzuar Abdul Rahim, Hazwani Ahmad Yusof, Ying Hou

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liping ZhouDepartment of Community Health, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, 13200, Malaysia.
Huaide ChuDepartment of Rehabilitation Medicine, Kunshan NO.4 People's Hospital, Kunshan, 215300, China.
Manting CaoDepartment of Community Health, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, 13200, Malaysia.
Nur Arzuar Abdul RahimDepartment of Clinical Medicine, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, 13200, Malaysia.
Hazwani Ahmad YusofDepartment of Community Health, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Kepala Batas, Pulau Pinang, 13200, Malaysia. hazwanihanafi@usm.my.ORCID http://orcid.org/0000-0001-6600-8425
Ying HouThe Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, 215008, China. horae1023@hotmail.com.

Funding

Gusu School of Nanjing Medical University GSKY20240206
6 · The paper itself

Abstract

backgroundModified Constraint-Induced Movement Therapy (mCIMT) has demonstrated significant potential in rehabilitating lower extremity motor impairments following stroke. However, mCIMT's application is often limited by the need for specialized devices to constrain the non-affected extremity and longer training duration. Constraint Standing Training (CST) is a novel variation of mCIMT that addresses these limitations by eliminating the need for constraining devices and reducing training time, thereby enhancing its feasibility for clinical implementation. Despite these advantages, the specific effects of CST on balance and gait in stroke patients remain underexplored.

methodsThis study will use a randomized, controlled, single-blinded design. Fifty stroke patients in the chronic phase, with gait disabilities and the ability to stand independently, will be randomly assigned to either the CST group or a control group using a computer-generated randomization sequence. Exclusion criteria include physiological or cognitive impairments that may hinder evaluation or training. Both groups will undergo daily 1-h training sessions, five times per week, for 8 weeks. The CST group will undergo sequential standing training using shaping strategies from a single plane to multiple planes, while the control group will receive conventional intensive training, which includes balance and gait exercises commonly used in clinical practice. Assessments will be carried out at baseline (T DISCUSSION: This protocol provides detailed CST methods to guide future research and clinical application. The study employs a randomized controlled trial design to robustly evaluate CST's effects on balance and gait in hemiparetic stroke patients. CST's sequential, multi-plane exercises offer a potentially practical alternative. However, larger, multi-center trials are recommended for future validation.

trial registrationThis trial is registered at www.chictr.org.cn . REGISTRATION NUMBER: ChiCTR2400086282. Date of registration: 27 June 2024.

Indexed as

Constraint Induced Movement TherapyGaitParesisPostural BalanceStrokeStroke RehabilitationAdultAgedFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicRecovery of FunctionSingle-Blind MethodTime FactorsBalanceConstraint Standing TrainingExercise therapyGait analysisHemiplegiaModified constraint-induced movement therapyStroke

Identifiers

PMID42035149
PMCPMC13261917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.