Evidence map›Paper›PMID 42034845›Full record

ArticleScientific reports2026

Emergence and predominance of GII.17[P17] noroviruses in Brazil, 2023-2024.

Fábio Correia Malta, Mateus de Souza Mello, Ighor Arantes, Juliana da Silva Ribeiro de Andrade, Alexandre Madi Fialho, Gabriel Assad Baduy, Rafael Brandão Varella, Maria Angelica Arpon Marandino Guimarães, Fernanda Marcicano Burlandy, Tulio Machado Fumian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fábio Correia MaltaLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil.
Mateus de Souza MelloLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil.
Ighor ArantesLaboratory of Arboviruses and Hemorrhagic Viruses, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Juliana da Silva Ribeiro de AndradeLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil.
Alexandre Madi FialhoLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil.
Gabriel Assad BaduyLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil.
Rafael Brandão VarellaDepartment of Microbiology and Parasitology, Institute Biomedical, Federal Fluminense University, Niterói, 24210-130, Brazil.
Maria Angelica Arpon Marandino GuimarãesDepartment of Infectious and Parasitic Diseases, School of Medicine, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-590, Brazil.
Fernanda Marcicano BurlandyLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil.
Tulio Machado FumianLaboratory of Comparative and Environmental Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, 21045-900, Brazil. tuliomf@ioc.fiocruz.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Norovirus is a leading cause of acute gastroenteritis (AGE) worldwide, affecting all age groups. In the present study, we investigated fecal samples from medically attended AGE patients received from ten Brazilian states collected during 2023 and 2024. Norovirus GI and GII were detected and quantified using RT-qPCR, and norovirus-positive samples underwent genotyping through sequencing the ORF1/2 junction region. During the two-year period, norovirus prevalence was 22.5%. GII genotypes were predominant, accounting for 85.6% of the genotyped samples. By genotyping, we detected the circulation of 19 norovirus genotypes, of which the emergence of GII.17[P17] in 2023 and its predominance in 2024. Comparison of cycle threshold (Ct) values indicated that the median viral load was significantly higher for norovirus GII.17 compared to GII.4 (20.9 and 22.3, respectively (p = 0.0493). Additionally, we showed that GII.17 patients were older compared to GII.4 patients. Our study is the first in South America to demonstrate replacement of the previous dominant genotype (GII.4 Sydney[P16]) to GII.17[P17] in 2024, currently disseminated worldwide.

Indexed as

Caliciviridae InfectionsGastroenteritisNorovirusBrazilFecesGenotypeHumansPhylogenyPrevalenceViral Load

Identifiers

PMID42034845
PMCPMC13365198

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.