ArticleSleep & breathing = Schlaf & Atmung2026
Prevalence of comorbid Insomnia and sleep apnoea (COMISA) in patients with obesity hypoventilation syndrome.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Combined Airway and Bariatric Surgery for Obesity Hypoventilation Syndrome: Feasibility and Early Outcomes-A Prospective Observational Cohort Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity hypoventilation syndrome (OHS) frequently coexists with obstructive sleep apnoea (OSA), but the prevalence of comorbid insomnia and sleep apnoea (COMISA) in patients with OHS is uncertain. We aimed to determine COMISA prevalence in OHS and to describe the associated clinical and polysomnographic features.
methodsAdults with OSA ± OHS were included. Demographics, comorbidities, daytime arterial blood gases, polysomnography variables, structured sleep-questionnaire responses, and the Epworth Sleepiness Scale (ESS) score were noted.
resultsWe analysed 3,215 patients (516 with OHS, 2,699 with pure OSA; age:50.3 ± 12.0 years; female/male: 1,030/2,185). The prevalence of COMISA was higher in OHS than in pure OSA (32.0% vs. 22.6% p < 0.001). Within the OHS group, COMISA was associated with a higher apnoea–hypopnoea index, oxygen desaturation index, arousal index, and ESS score (all p < 0.001), as well as a higher prevalence of hypertension, diabetes mellitus, and heart failure (p < 0.001, p = 0.002, and p = 0.005, respectively). OHS patients with COMISA also had more severe OSA than COMISA patients alone did (p < 0.001). COMISA in OHS patients was independently associated with higher daytime arterial partial pressure of carbon dioxide (PaCO₂) (adjusted OR [aOR] 1.299; 95% CI 1.198–1.409; p < 0.001), more severe OSA (aOR 2.419; 95% CI 1.288–4.543; p = 0.006), higher ESS score (aOR 1.104; 95% CI 1.047–1.163; p < 0.001).
conclusionsCompared with pure OSA group, COMISA is more common in OHS. High daytime PaCO₂ was independently associated with COMISA in OHS. OHS patients with COMISA also had more fragmented sleep, greater OSA severity, a higher ESS score and a higher prevalence of comorbidities.
Indexed as
Identifiers
42034803What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.