ArticleScientific reports2026
Supportive neural mechanisms underlying successful emotion regulation for reappraisal success.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the prefrontal cortex (PFC) is well-known for its role in emotion regulation, the interactions between cortical and subcortical regions that facilitate this process remain incompletely understood. The present study aims to enhance our understanding of the brain pathways and connectivity involved in emotion regulation. Thirty healthy, right-handed participants were presented with a total of 48 aversive images characterized by low normative valence and high arousal, along with 24 neutral photos. The preprocessing pipeline included slice timing correction, motion correction, structural alignment, and denoising. Connectivity analyses were performed using ROI-to-ROI, seed-to-voxel, voxel-to-voxel, and amplitude of low-frequency fluctuations (ALFF) approaches within FSL and the CONN toolbox to evaluate brain activation. Our results indicated that instructed cognitive reappraisal was associated with increased activation in the dorsolateral PFC (dlPFC) and decreased activation in the ventromedial PFC (vmPFC). Functional connectivity analyses further revealed coordinated activity among the PFC and anterior cingulate regions during reappraisal. Cognitive reappraisal highlights the roles of the dlPFC, vlPFC, vmPFC, ACC, and amygdala in emotion regulation and executive control. These findings provide descriptive support for prefrontal cortex involvement in emotion regulation and are partially consistent with previously proposed dual-pathway frameworks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.