Evidence map›Paper›PMID 42034098›Full record

ArticleJACC. Advances2026

Design of the School-Based SI! Program Reintervention Trial for Child Health Promotion.

Gloria Santos-Beneit, Amaya de Cos-Gandoy, Patricia Bodega, Xavier Orrit, Carla Rodríguez, Mercedes de Miguel, Natalia Montilla, Juan Miguel Fernández-Alvira, Jesús Martínez-Gómez, Raquel Diaz-Muñoz and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in JACC. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06715358 (Cluster Randomized Trial for the SI! Program Reintervention for Elementary Schools), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06715358 narecruitingnot on this map

Cluster Randomized Trial for the SI! Program Reintervention for Elementary Schools

TypeinterventionalSponsorFoundation for Science, Health and Education, SpainRan2023 to 2031Enrolled840ConditionsCardiovascular Health, ObesityArmsReintervention, Late intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Gloria Santos-BeneitSHE Foundation (Science, Health, and Education), Barcelona, Spain; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Amaya de Cos-GandoySHE Foundation (Science, Health, and Education), Barcelona, Spain; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Patricia BodegaSHE Foundation (Science, Health, and Education), Barcelona, Spain; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Xavier OrritSHE Foundation (Science, Health, and Education), Barcelona, Spain.
Carla RodríguezSHE Foundation (Science, Health, and Education), Barcelona, Spain.
Mercedes de MiguelSHE Foundation (Science, Health, and Education), Barcelona, Spain; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Natalia MontillaSHE Foundation (Science, Health, and Education), Barcelona, Spain.
Juan Miguel Fernández-AlviraCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Jesús Martínez-GómezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Raquel Diaz-MuñozHospital Universitario Clínico San Carlos, IdISSC, Madrid, Spain.
Domenec HaroSHE Foundation (Science, Health, and Education), Barcelona, Spain.
Carles PeyraSHE Foundation (Science, Health, and Education), Barcelona, Spain; Mount Sinai Fuster Heart Hospital, New York, New York, USA.
Isabel CarvajalSHE Foundation (Science, Health, and Education), Barcelona, Spain.
Rodrigo Fernandez-JimenezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Hospital Universitario Clínico San Carlos, IdISSC, Madrid, Spain; Centro de Investigación Biomédica En Red en enfermedades CardioVasculares (CIBERCV), Madrid, Spain. Electronic address: rodrigo.fernandez@cnic.es.
Valentin FusterSHE Foundation (Science, Health, and Education), Barcelona, Spain; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Mount Sinai Fuster Heart Hospital, New York, New York, USA. Electronic address: valentin.fuster@mountsinai.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SI! Program is a long-term, school-based intervention promoting cardiovascular health across multiple age groups. This article presents the design of a new cluster-randomized controlled trial incorporating a reintervention to strengthen sustainability and promoting a school-family approach. A total of 977 children (age 6.2 years, 51.6% girls) from 50 schools in Spain were recruited. Schools were randomized to a reintervention group (intervention in second grade and reintervention in fifth grade) or a single-intervention group (intervention only in fifth grade). The primary endpoint is the change in the SI!-Child score-diet, physical activity, sleep health, and body mass index-between baseline and 5-year follow-up. The secondary endpoints include 5-year changes in SI!-Child subcomponents, sedentarism, adiposity, and the Life's Essential 8 score and subcomponents. This revised SI! Program builds on insights from earlier trials, emphasizing adherence and long-term behavior change through a reintervention combined with active engagement of the school community and families. (The SI! Program Reintervention for Elementary Schools Trial [PSIR]; NCT06715358).

Indexed as

cardiovascular health scorechild health promotionschool environment

Identifiers

PMID42034098
PMCPMC13129425

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.