ReviewEarly human development2026
Retinopathy of prematurity: Moving beyond oxygen.
Review in Early human development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
Abstract
Retinopathy of prematurity (ROP) is a vision-threatening disease among very preterm newborns in high-income countries and also in gestationally older newborns in low resource settings. The main classic risk factor and purported causal culprit is exogenous oxygen, which regulates angiogenic growth factors in the two phases of the disease. Along these lines, the vast majority of animal studies use oxygen-induced retinopathy models, with very limited data coming from non-oxygen models. We make the case in favor of alternative etiological paradigms and call for more models that employ infection and inflammation-associated exposures. We support our argument by reference to recent experimental and clinical data.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.