ArticleJournal of neuro-oncology2026
Variation in rates of post-operative oncological treatment for patients with glioblastoma in England: a comprehensive multi-year National cohort study from the GlioCova project.
Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Trends in Treatment and Survival Among Patients with Glioblastoma in the United States from 2000 to 2020.Cancers · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeAlthough there are consistent guidelines of standardised glioblastoma patient care, there may be variation in treatments delivered due to differences in patient characteristics or adherence to guidelines across centres. This study explores the variation in treatments for glioblastoma patients across centres in a comprehensive multi-year brain tumour patient cohort in England.
methodsWe analysed data from the Gliocova project that contains over 50,000 adult brain tumour patients diagnosed between 2013 and 2018 in England. We selected a glioblastoma patient cohort and explored treatment rates, systemic predictors of treatment, variation in treatment across surgical centres and survival rates for different treatment groups.
resultsWe analysed data from 11 359 patients with a histological diagnosis of GBM. Almost 80% of glioblastoma patients received at least some treatment after brain surgery, with 40% receiving the guideline recommended aggressive treatment (47% in the under-70s cohort). Age, sex, deprivation status, comorbidities, surgery type (resection versus biopsy) and ethnicity were identified as systemic predictors of receipt of post-operative treatment. There was also variation in receipt of post-operative treatment (64%-86%) and receipt of aggressive treatment (16%-65%) across centres. Patients receiving aggressive treatment had highest survival (15.6 months); in patients receiving any post operative treatment survival was 12.5 months and in patients receiving surgery only survival was 2.5 months.
conclusion22% of glioblastoma patients undergoing surgery receive no further treatment and there is variation in post-surgical treatment both at centre and individual patient level. We suggest that centres should measure and report rates of no further treatment as part of standard clinical governance.
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