ArticleMarine biotechnology (New York, N.Y.)2026
Physiological and Metabolic Responses to Graded Dietary Biotin Supplementation in Juvenile Penaeus vannamei.
Article in Marine biotechnology (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biotin serves as a coenzyme in carboxylation reactions and plays a fundamental role in supporting growth, nutrient metabolism and overall physiological function in aquatic animals. This study investigated the biochemical and metabolic responses of graded dietary biotin in Penaeus vannamei. Five experimental diets were prepared with graded biotin supplementation levels of 0, 2, 4, 6 and 8 mg/kg (designated as Con, B02, B04, B06 and B08, respectively). The corresponding analyzed biotin concentrations were 1.65, 3.76, 5.84, 8.14 and 10.41 mg/kg, respectively. Twenty shrimp (0.55 ± 0.01 g) were randomly stocked into each tank, with four replicate tanks assigned to each experimental diet. The shrimp were fed the diets six times daily for 6 weeks. Dietary biotin supplementation significantly increased growth and improved feed utilization and protein efficiency ratio. Survival was not affected by the dietary treatment during the feeding trial. Whole-body lipid decreased linearly with increasing dietary biotin concentration. Hepatopancreatic biotin concentration exhibited a significant linear increase with graded dietary biotin concentrations. Chymotrypsin, lipase and amylase activities and intestinal villi height showed significant quadratic responses to dietary biotin concentration. Lysozyme activity increased linearly with dietary biotin concentrations, while antiprotease activity was significantly elevated in B02, B04 and B06 groups compared to Con group. Superoxide dismutase activity was significantly elevated in all biotin-supplemented groups. Based on piece-wise regression analysis, the optimal dietary biotin concentration for growth and feed conversion ratio was estimated at 3.09 to 3.66 mg/kg, respectively.
Indexed as
Identifiers
42033479What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.