Evidence map›Paper›PMID 42033331›Full record

ArticleThe FEBS journal2026

Water, water, every where-the advent of hydrated pili structure.

Hiroya Oki, Hideki Shigematsu, Kazuki Kawahara, Christoph Gerle

Abstract read
In one paragraph

Article in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hiroya OkiResearch Institute for Microbial Diseases, The University of Osaka, Suita, Japan.
Hideki ShigematsuDiffraction and Scattering Division, Japan Synchrotron Radiation Research Institute, SPring-8 Center, Sayo, Japan.ORCID https://orcid.org/0000-0003-3951-8651
Kazuki KawaharaGraduate School of Pharmaceutical Sciences, The University of Osaka, Suita, Japan.ORCID https://orcid.org/0000-0003-3909-1512
Christoph GerleLife Science Research Infrastructure Group, RIKEN SPring-8 Center, Sayo, Japan.ORCID https://orcid.org/0000-0002-7265-2804

Funding

Japan Agency for Medical Research and Development (AMED) JP25ama121001Japan Society for the Promotion of Science 21K07024
6 · The paper itself

Abstract

Protein structure is defined by its surrounding water. Naturally, this is also true for the gigantic protein filaments that pathogenic bacteria use to attach to and colonize their host cells. Structures of these filaments for which water can be identified with high confidence have stayed elusive for the longest time. In this issue of The FEBS Journal, Petrova et al. unveil the first fully hydrated Type I pilus structure from uropathogenic E. coli. In a powerful showcase of the current capabilities of cryo-EM, their structure beautifully visualizes internal water channels that traverse the pilus, thus marking the advent of hydrated pilus structural biology.

Indexed as

Fimbriae, BacterialUropathogenic Escherichia coliWaterCryoelectron MicroscopyHumansWaterbacterial filamenthelical reconstructionpublic use cryo‐EMuropathogenic E. coliwater

Identifiers

PMID42033331
PMCPMC13628539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.