Evidence map›Paper›PMID 42033094›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

The role of life-course socioeconomic position in cognitive change and mild cognitive impairment among middle-aged and older US Hispanic/Latinos.

Paola Filigrana, Melissa Lamar, Monica Batalha, Jee-Young Moon, Wassim Tarraf, Richard B Lipton, Linda C Gallo, Martha L Daviglus, Krista M Perreira, Ariana M Stickel and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Paola FiligranaDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-8297-3943
Melissa LamarRush Alzheimer's Disease Center and the Department of Psychiatry and Behavioral Sciences, Rush University, Chicago, Illinois, USA.
Monica BatalhaDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Jee-Young MoonDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Wassim TarrafDepartment of Healthcare Sciences, Institute of Gerontology, Wayne State University, Detroit, Michigan, USA.
Richard B LiptonDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Linda C GalloDepartment of Psychology, San Diego State University, San Diego, California, USA.
Martha L DaviglusInstitute for Minority Health Research, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Krista M PerreiraDepartment of Social Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ariana M StickelDepartment of Psychology, San Diego State University, San Diego, California, USA.
Fernando D TestaiDepartment of Neurology and Rehabilitation, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Bharat ThyagarajanDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
Hector M GonzalezDepartment of Neurosciences, University of California, San Diego, California, USA.
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.

Funding

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50P50HD105352 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Julie Secombe · 2021 to 2026
$7.0M
Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)R01AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GONZALEZ, HECTOR M · 2015 to 2019
$5.7M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
Early and life course socioeconomic adversity and dementia risk in Hispanics/LatinosR01AG077639 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2025 to 2025
$451k
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
Alzheimer's Association HHSN268201300003IAlzheimer's Association N01-HC65233Alzheimer's Association N01-HC65234Alzheimer's Association N01-HC65235Alzheimer's Association N01-HC65236Alzheimer's Association N01-HC65237NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS N01-HC65237NIA NIH HHS 4R01AG077639NIA NIH HHS R01 AG048642NIA NIH HHS R01AG048642NIA NIH HHS R01 AG062711NIA NIH HHS R01AG062711NIA NIH HHS R01 AG077639NICHD NIH HHS P50 HD105352NIDCD NIH HHSNIDCR NIH HHSNIDDK NIH HHSNIMHD NIH HHSNINDS NIH HHSOffice of Dietary Supplements
6 · The paper itself

Abstract

introductionThe role of life-course socioeconomic position (SEP) in cognitive aging remains unclear. We assessed the association between life-course SEP with cognitive change and prevalent mild cognitive impairment (MCI).

methodsWe used data from the Hispanic Community Health Study/Study of Latinos (2008 to 2011) and its Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA) ancillary study (2015 to 2018, n = 6351; aged ≥45 years). Weighted linear and logistic regression analyses estimated the association between childhood and adult SEP (low and high) and socioeconomic mobility (enduring high or low SEP, upward or downward mobility) with change in cognitive function and prevalent MCI, respectively.

resultsChildhood SEP was associated with greater adverse cognitive change but was not associated with prevalent MCI. Low adult SEP, downward mobility, and enduring low SEP were associated with greater adverse cognitive change. Enduring low SEP was additionally associated with higher odds of MCI. DISCUSSION: Life-course SEP is associated with changes in cognitive aging in middle-aged and older Hispanic/Latino adults.

Indexed as

Cognitive AgingCognitive DysfunctionHispanic or LatinoSocioeconomic FactorsAgedFemaleHumansLow Socioeconomic StatusMaleMiddle AgedSocioeconomic Disparities in HealthUnited Statesadultscognitive changecognitive functionHispanicsLatinolife coursemild cognitive impairmentsocioeconomic mobilitysocioeconomic position

Identifiers

PMID42033094
PMCPMC13109640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.