Evidence map›Paper›PMID 42033021›Full record

ArticleAnnals of the American Thoracic Society2026

Food insecurity is associated with COPD prevalence and mortality: evidence from U.S. county-level data.

Katherine E Goodenberger, Swaraj Bose, Susan K Murray, Christopher B Bosma, MeiLan K Han, Jeffrey L Curtis, Wassim W Labaki

Abstract read
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Article in Annals of the American Thoracic Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Katherine E GoodenbergerDepartment of Internal Medicine, Washington University School of Medicine, Saint Louis, MO, United States.
Swaraj BoseDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, United States.
Susan K MurrayDepartment of Biostatistics, University of Michigan, Ann Arbor, MI, United States.
Christopher B BosmaDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0001-7438-7453
MeiLan K HanDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, United States.
Jeffrey L CurtisDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, United States.
Wassim W LabakiDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, United States.ORCID 0000-0002-3203-5537

Funding

Defining Pathways in COPD Patient Oriented ResearchK24HL138188 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MeiLan K Han · 2017 to 2026
$1.2M
Leveraging Serum Metabolomics to Understand Clinical Phenotypes in COPDK23HL151751 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LABAKI, WASSIM W · 2020 to 2024
$875k
NHLBI NIH HHS K23 HL151751NHLBI NIH HHS K24 HL138188NIH HHS K23HL151751Respiratory Health AssociationSolovy Award for Advancement in COPD
6 · The paper itself

Abstract

rationaleAlthough unreliable access to healthy food has been linked to lower lung function, a higher burden of respiratory symptoms, and more frequent respiratory exacerbations in individuals with COPD, its association with COPD prevalence and mortality remains understudied.

objectiveTo determine the associations between food insecurity and COPD prevalence and COPD mortality at the county level in the United States.

methodsWe obtained 2018 U.S. county-level data on food insecurity prevalence (FI%) and the Food Environment Index (FEI; lower values indicate worse food desert conditions) from County Health Rankings. We then queried the CDC's National Environmental Public Health Tracking and WONDER databases for county-level COPD prevalence (2018) and COPD-related mortality (2018-2020), respectively. We constructed negative binomial regression models adjusted for demographic, socioeconomic, and health factors to examine the associations of FI% and FEI with COPD prevalence and mortality. The mortality model was additionally adjusted for county COPD prevalence.

resultsCounties with FI% at or above the median (13.2%) and those with FEI below the median (7.6) had lower median household income, lower primary care physician density, higher average daily PM2.5 concentration, and higher prevalence of poverty, uninsured status, rural residence, and cigarette smoking (P < .001 for all analyses). In fully adjusted models, a 1% higher FI% was associated with a 1.62% higher COPD prevalence (95% CI 1.40%-1.83%; P < .001), and a 1-unit lower FEI was associated with a 1.85% higher COPD prevalence (95% CI 1.17%-2.54%; P < .001). A 1% higher FI% was independently associated with a 3.54% increase in COPD-related mortality (95% CI 2.86%-4.22%; P < .001), and a 1-unit lower FEI with a 10.05% increase in COPD-related mortality (95% CI 7.82%-12.27%; P < .001).

conclusionUnreliable food access is associated with higher COPD prevalence and mortality at the county level. These results suggest that improving food access may be a target for improving population-level COPD outcomes.

Indexed as

Food InsecurityPulmonary Disease, Chronic ObstructiveAgedFemaleHumansMalePrevalenceUnited StatesCOPDepidemiologyfood desertfood insecurity

Identifiers

PMID42033021
PMCPMC13359219

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.