Evidence map›Paper›PMID 42033009›Full record

ArticleEnvironmental and molecular mutagenesis2026

Alizarin Dye: Toxicity, Genotoxicity, and Histopathological Alterations in Model Organisms.

Amanda Rocha Rodrigues, Gabriela Cristina Fonseca Almeida, Natália Oliveira de Farias, Anjaina Fernandes de Albuquerque, Adria Caloto de Oliveira, Jessica Camila Miranda Cardoso, Gabriely Fernanda Groto Militão, Inês Moutinho Cabral, Catarina A Faustino, João D Vitorino and 3 more

Abstract read
In one paragraph

Article in Environmental and molecular mutagenesis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Synthesis of ZnO, FeRSC advances · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Amanda Rocha RodriguesFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Gabriela Cristina Fonseca AlmeidaFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Natália Oliveira de FariasFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Anjaina Fernandes de AlbuquerqueFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Adria Caloto de OliveiraFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Jessica Camila Miranda CardosoFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Gabriely Fernanda Groto MilitãoFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Inês Moutinho CabralAssociate Laboratory i4HB Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University of Lisbon, Caparica, Portugal.ORCID 0000-0002-7628-8747
Catarina A FaustinoAssociate Laboratory i4HB Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University of Lisbon, Caparica, Portugal.
João D VitorinoAssociate Laboratory i4HB Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University of Lisbon, Caparica, Portugal.
Marina Tenório BotelhoFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.
Pedro M CostaAssociate Laboratory i4HB Institute for Health and Bioeconomy, NOVA School of Science and Technology, NOVA University of Lisbon, Caparica, Portugal.
Gisela de Aragão UmbuzeiroFaculdade de Tecnologia, Universidade Estadual de Campinas, Limeira, Brazil.ORCID 0000-0002-8623-5200

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/01204-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2022/04482-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/07768-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2023/18005-0Fundação para a Ciência e a Tecnologia LA/P/0140/2020Fundação para a Ciência e a Tecnologia UIDP/04378/2020+UIDB/04378/2020
6 · The paper itself

Abstract

Alizarin is an anthraquinone red dye from natural or synthetic sources, widely used in textiles. Effluents of this activity can contain residual dyes, which may contaminate the aquatic environment. Studies report alizarin's aquatic toxicity, mutagenic, and carcinogenic effects. This study aimed to complement the aquatic toxicity evaluation and confirm its ability to cause genotoxicity in alternative models. Acute toxicity was performed with crustaceans, mussels, and fish embryos, while chronic toxicity was assessed in algae. Light effects on toxicity were evaluated using Daphnia similis. Histopathological effects on the gonads of Mytilus galloprovincialis and somatic mutations and sperm genotoxicity in Parhyale hawaiensis were investigated. Mutagenicity was confirmed using a miniaturized Ames test. The effect concentration 50% (EC

Indexed as

AnthraquinonesColoring AgentsDNA DamageMutagensWater Pollutants, ChemicalAnimalsDaphniaEmbryo, NonmammalianGonadsMaleMutagenicity TestsMytilusSpermatozoaZebrafishalizarinAnthraquinonesColoring AgentsMutagensWater Pollutants, ChemicalanthraquinonesDNA damageecotoxicitygonadshemocytessperm cells

Identifiers

PMID42033009
PMCPMC13109681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.