Evidence map›Paper›PMID 42032956›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2026

[Safety and efficacy of pulsed radiofrequency therapy for zoster-associated trigeminal neuralgia under general anesthesia].

Junjie Zhang, Suyu Feng, Wangyuan Zou, Zhuoyi Liu, E Wang, Jianqin Yan, Nianyue Bai, Shenghui Yang, Jiangang Luo, Fei Ren

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junjie ZhangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008. junjie_zhang@csu.edu.cn.
Suyu FengDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Wangyuan ZouDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Zhuoyi LiuDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
E WangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Jianqin YanDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Nianyue BaiDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Shenghui YangDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Jiangang LuoDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008.
Fei RenDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008. 670224839@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPulsed radiofrequency (PRF) treatment of the trigeminal ganglion via foramen ovale puncture for zoster-associated trigeminal neuralgia typically requires patient feedback during sensory and motor stimulation, and is usually performed under regional anesthesia (RA). However, under RA, patients often experience poor comfort due to pain and anxiety during puncture and PRF, and severe pain occurs when adjusting needle position or increasing output voltage. This often leads to lower-than-optimal treatment voltages, poor patient cooperation, and sometimes interruption or refusal of treatment. The Department of Anesthesiology at Xiangya Hospital, Central South University, has performed CT-guided trigeminal ganglion PRF under general anesthesia (GA) for zoster-associated trigeminal neuralgia. Currently, no studies directly compare the efficacy and safety of GA versus RA for this procedure. This study aims to compare GA and RA in terms of safety and efficacy for trigeminal ganglion PRF treatment of zoster-associated trigeminal neuralgia, providing clinical guidance for optimal anesthesia choice.

methodsData were retrospectively collected for hospitalized and treated with trigeminal ganglion PRF for zoster-associated trigeminal neuralgia at Xiangya Hospital, Central South University, from July 2022 to January 2025. Patients were grouped according to the anesthesia method used during PRF: GA group and RA group. Baseline characteristics (demographics, comorbidities, disease features) were compared between groups. Pain was assessed using the Visual Analogue Scale (VAS) at 1 day, 1 month, 3 months, and 6 months postoperatively, and changes from baseline were analyzed. Patient satisfaction, total hospitalization duration, direct medical costs, and perioperative complications (hypertension, hypotension, bradycardia, tachycardia, etc.) were also compared.

resultsA total of 61 patients were included (GA group,

conclusionsGA and RA provide comparable efficacy for trigeminal ganglion PRF in zoster-associated trigeminal neuralgia. However, GA significantly improves patient satisfaction and reduces cardiovascular stress without increasing other postoperative complications. PRF under GA is safe and feasible.

Indexed as

Anesthesia, GeneralPulsed Radiofrequency TreatmentTrigeminal NeuralgiaAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeTrigeminal Ganglioncardiovascular stressgeneral anesthesiapulsed radiofrequencyregional anesthesiatrigeminal ganglionzoster-associated trigeminal neuralgia

Identifiers

PMID42032956
PMCPMC13071590

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.