Evidence map›Paper›PMID 42032867›Full record

ArticleBriefings in bioinformatics2026

Discussions on the generalization of HybridSP on more equivalent benchmarks.

Zhihao Wang, Sheng Wang, Jingjing Guo, Yuguang Mu, Xiangdong Liu, Liangzhen Zheng, Weifeng Li

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhihao WangSchool of Physics, Shandong University, 27 Shanda Nan Road, Jinan, Shandong Province 250100, China.
Sheng WangShanghai Zelixir Biotech Co. Ltd., 298 Xiangke Road Shanghai 201210, China.
Jingjing GuoCentre for Artificial Intelligence Driven Drug Discovery, Faculty of Applied Science, Macao Polytechnic University, R. de Luís Gonzaga Gomes, Macao 999078, China.ORCID 0000-0002-4632-4364
Yuguang MuSchool of Biological Sciences, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.ORCID 0000-0002-2499-026X
Xiangdong LiuSchool of Physics, Shandong University, 27 Shanda Nan Road, Jinan, Shandong Province 250100, China.
Liangzhen ZhengShanghai Zelixir Biotech Co. Ltd., 298 Xiangke Road Shanghai 201210, China.ORCID 0000-0003-1179-2106
Weifeng LiSchool of Physics, Shandong University, 27 Shanda Nan Road, Jinan, Shandong Province 250100, China.

Funding

National Key R&D Program of China 2023YFA0915500National Natural Science Foundation of China 12574225Taishan Scholars Program of Shandong Province tstp20240807
6 · The paper itself

Abstract

We thank the reviewers for their thoughtful comments and we have carefully addressed the concerns raised. In our response, we clarify key methodological aspects and provide additional analyses to improve the transparency and rigor of our work. Importantly, we further evaluate the model on more diverse and fair benchmarks beyond the original setting, demonstrating its robustness and generalization ability. These additions strengthen the overall conclusions and provide a more comprehensive assessment of HybridSP.

Indexed as

BenchmarkingComputational BiologyProteinsSoftwareAlgorithmsLigandsLigandsProteinsprotein-ligand interactionscoring functionstatistical potential

Identifiers

PMID42032867
PMCPMC13109047

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.