Evidence map›Paper›PMID 42032697›Full record

ArticleVirology journal2026

The phage Φ13-encoded transcriptional regulator Ltr controls phage assembly in Staphylococcus aureus.

Ronja Dobritz, Marcel Bäcker, Carina Rohmer, Natalya Korn, Vittoria Bisanzio, Christiane Wolz

Abstract read
In one paragraph

Article in Virology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ronja DobritzInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
Marcel BäckerInstitute of Biodiversity, Ecology and Evolution, Cluster of Excellence "Balance of the Microverse", Friedrich Schiller University, Jena, Germany.
Carina RohmerInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
Natalya KornInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
Vittoria BisanzioInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany.
Christiane WolzInterfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany. christiane.wolz@uni-tuebingen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTemperate phages play a central role in the evolution and pathogenicity of Staphylococcus aureus. Sa3int phages provide highly human-specific virulence factors that promote immune evasion and survival within the host. The reversible excision of these phages which occurs without phage production and bacterial lysis allows the simultaneous expression of phage virulence genes and the hlb gene where they usually integrate. However, the regulatory mechanisms that control phage assembly and the cross-talk with host factors remain poorly understood. METHODS AND

resultsWe analyzed the regulatory mechanism controlling late gene transcription of Sa3int phage Φ13. We identified a functional promoter, P

conclusionsLtr controls the expression of late phage genes, thereby regulating phage assembly and lysis. This process is modulated by SpoVG activity.

Indexed as

Gene Expression Regulation, ViralStaphylococcus aureusStaphylococcus PhagesTerminal Repeat SequencesVirus AssemblyPromoter Regions, GeneticTranscription, GeneticViral ProteinsViral ProteinsActive lysogenyLate transcriptional regulatorsPhage assemblyPseudo-lysogenyStaphylococcus aureus

Identifiers

PMID42032697
PMCPMC13123087

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.