Evidence map›Paper›PMID 42032660›Full record

ArticleJournal of orthopaedic surgery and research2026

Meniscal centralization restores meniscus-cartilage contact mechanics after posterior root repair: a biomechanical in-silico study.

Yongwei Zhou, Qinglin Lu, Jiajing Xu, Lijunpeng Jia, Congcong Wu, Qining Yang, Jingchi Li

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Article in Journal of orthopaedic surgery and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Yongwei ZhouDepartment of Orthopedics, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, People's Republic of China.
Qinglin LuDepartment of Orthopedics, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, People's Republic of China.
Jiajing XuDepartment of Orthopedics, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, People's Republic of China.
Lijunpeng JiaDepartment of Orthopedics, Luzhou Key Laboratory of Orthopedic Disorders, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, People's Republic of China.
Congcong WuDepartment of Orthopedics, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, People's Republic of China.
Qining YangDepartment of Orthopedics, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, People's Republic of China. jhszxyyyqn@163.com.
Jingchi LiDepartment of Orthopedics, Luzhou Key Laboratory of Orthopedic Disorders, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, People's Republic of China. lijingchi9405@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMeniscal posterior root tears can be effectively treated with root repair surgery. However, this isolated approach often fails to correct concomitant meniscal extrusion. Meniscal centralization has therefore emerged as a solution to address this limitation. Despite preliminary clinical evidence showing that centralization can delay knee osteoarthritis (KOA) progression over two years, the biomechanical mechanism underlying this clinical benefit remains uninvestigated.

methodsWe constructed a knee joint finite element model using a well-established modeling strategy. After validating the model, we generated two surgical scenarios: isolated posterior root repair and repair combined with meniscal centralization. Under different directional compressive loads, we compared the maximum displacement of the medial meniscus and the corresponding contact area between the meniscus and the medial tibial cartilage.

resultsA consistent trend was observed under different directional compressive loads. Specifically, in the meniscus posterior root repair model, meniscus displacement increased while the contact area between the meniscus and tibial cartilage decreased. In contrast, although meniscus displacement in the centralization model was even lower than that in the control group, the contact area was comparable between the two models.

conclusionMeniscus centralization limits meniscal displacement, thereby reducing extrusion and increasing the contact area between the meniscus and tibial cartilage. These conclusions are biomechanical inferences drawn under the premise that the centralization surgery provides rigid constraint of the meniscus. They have not yet been validated by large-sample prospective clinical trials, an issue that should be addressed in subsequent studies.

Indexed as

Cartilage, ArticularComputer SimulationMenisci, TibialTibial Meniscus InjuriesBiomechanical PhenomenaFinite Element AnalysisHumansKnee osteoarthritisLoad transmissionMeniscus centralizationModel calibrationPosterior root injury

Identifiers

PMID42032660
PMCPMC13359410

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