Evidence map›Paper›PMID 42032621›Full record

ReviewJournal of cardiothoracic surgery2026

Real-time three-dimensional transesophageal echocardiography and three-dimensional printing: detection of multiple perivalvular leaks after mitral valve replacement-a case report and literature review.

Zhirong Wang, Qiuxian Wan, Chengming Fan, Qi Ai, Hong You, Tianli Zhao, Shijun Hu, Qin Wu

Abstract readCase ReportsReview
In one paragraph

Review in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhirong WangDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qiuxian WanDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Chengming FanDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qi AiDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hong YouDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Tianli ZhaoDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Shijun HuDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qin WuDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. wuqin2025@csu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate assessment of perivalvular leak (PVL) morphology following valve replacement remains a significant clinical challenge. Precise characterization of PVL anatomy is essential, as different leak patterns require distinct management strategies. We report a case in which two complementary imaging modalities—real-time three-dimensional (RT-3D) transesophageal echocardiography (TEE) and three-dimensional (3D) printing technology—were successfully utilized to evaluate PVL morphology and guide the subsequent surgical approach. CASE PRESENTATION: A 63-year-old woman with a history of mechanical mitral valve replacement was found to have a PVL on follow-up transthoracic echocardiography (TTE), but the number and morphology could not be fully determined. Initial 3D printing based on cardiac computed tomography angiography (CTA) depicted only one defect; however, subsequent RT-3D TEE revealed two adjacent leaks. Based on TEE findings, the 3D printing parameters were adjusted, allowing visualization of both leaks. These imaging results informed a tailored interventional strategy, and transcatheter closure of the mitral PVLs was successfully performed via left ventricular apical access under real-time TEE guidance.

conclusionsThe synergistic integration of RT-3D TEE with color Doppler and 3D printing technology offers complementary strengths in the morphological assessment of complex or multiple PVLs, highlighting its potential clinical value in selected challenging cases.

Indexed as

Echocardiography, Three-DimensionalEchocardiography, TransesophagealHeart Valve ProsthesisHeart Valve Prosthesis ImplantationMitral ValveMitral Valve InsufficiencyPostoperative ComplicationsPrinting, Three-DimensionalFemaleHumansMiddle AgedProsthesis FailureMultiple perivalvular leaksReal-time three-dimensional echocardiographyThree-dimensional printingTranscatheter paravalvular leak closure

Identifiers

PMID42032621
PMCPMC13255269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.