Evidence map›Paper›PMID 42032603›Full record

ArticleReproductive health2026

Birth sex ratio in Western Sydney during the COVID-19 pandemic: associations by maternal country of birth.

Lieu Thi Thuy Trinh, Hassan Assareh, Michael Piza, Veth Guevara, Sabrina Naz, Kylie Smythe, Seng Chai Chua, Kathy Eljiz

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Article in Reproductive health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lieu Thi Thuy TrinhWestern Sydney Local Health District, Sydney, Australia. Lieu.Trinh@health.nsw.gov.au.ORCID http://orcid.org/0000-0002-6303-860X
Hassan AssarehNew South Wales Department of Health, Sydney, Australia.
Michael PizaWestern Sydney Local Health District, Sydney, Australia.
Veth GuevaraUniversity of Sydney, Sydney, Australia.
Sabrina NazWestern Sydney Local Health District, Sydney, Australia.
Kylie SmytheWestern Sydney Local Health District, Sydney, Australia.
Seng Chai ChuaWestern Sydney Local Health District, Sydney, Australia. S.Chua@westernsydney.edu.au.
Kathy EljizWestern Sydney Local Health District, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe sex ratio at birth (SRB)—the proportion of male to female births—is a vital demographic indicator with implications for societal stability. SRB can be influenced by a range of factors including socio-economic conditions, parental health, cultural preferences, with acute population-level stress recognised as a highly significant influence. This study examined temporal changes in SRB during the COVID-19 pandemic and associated maternal factors in a large, multicultural population.

methodsBirth data from women residing in the Western Sydney Local Health District (WSLHD) between 2016 and 2023 were analysed using multivariable logistic regression and time series analysis. Analyses adjusted for maternal demographic, socio-economic, health, and reproductive factors.

resultsOf 119,756 singleton births, 61,832 were male, resulting in a sex ratio at birth (SRB) of 0.516 (106.7 males per 100 females). No significant overall change in SRB was observed during the early post-pandemic period. The SRB during the 3–5 months following the onset of the COVID-19 pandemic increased only among births to Chinese mothers, as indicated in both time series analyses and logistic regression (SRB = 0.621 vs. 0.519; adjusted odds ratio [aOR] = 1.557; 95% CI: 1.194–2.030 compared to other periods). Other factors associated with an increased SRB included having an Indian mother (SRB = 0.524; adjusted odds ratio [aOR] = 1.038; 95% CI: 1.001–1.076), compared to having a non-Indigenous Australian mother (SRB = 0.516). Higher SRBs were also observed among mothers with one previous pregnancy (SRB = 0.519 vs. 0.513; aOR = 1.031; 95% CI: 1.004–1.059) or two previous pregnancies (SRB = 0.522; aOR = 1.050; 95% CI: 1.012–1.090), compared to mothers with no previous pregnancies. Conversely, mothers with hepatitis B had a lower SRB than those without the condition (SRB = 0.483 vs. 0.517; aOR = 0.858; 95% CI: 0.755–0.976).

conclusionsThe COVID-19 pandemic was not associated with an immediate aggregate shift in SRB in WSLHD. However, subgroup-specific variation by maternal country of birth was observed, highlighting the importance of maternal background in shaping SRB patterns. These findings underscore the need for culturally informed public health approaches in diverse populations during major societal disruptions.

Indexed as

COVID-19Sex RatioAdultFemaleHumansInfant, NewbornMaleNew South WalesPandemicsPregnancySARS-CoV-2Socioeconomic FactorsYoung AdultBirth sex ratioCOVID-19 pandemicImmigrantMulti-ethnicity

Identifiers

PMID42032603
PMCPMC13248341

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.