ArticleBMC musculoskeletal disorders2026
Clinical phenotypes of neuropathic pain and central sensitization in patients with knee osteoarthritis: demographic data, radiographic severity, and pain intensity.
Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Association of Neuropathic Pain with Function, Disease Severity, Emotional Status, Sleep Disturbance, and Quality of Life in Patients with Knee Osteoarthritis.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to simultaneously assess neuropathic pain (NP) and central sensitization (CS) in patients with knee osteoarthritis to determine their prevalence and identify patient characteristics associated with NP and CS based on demographic data, pain intensity, and radiographic severity commonly assessed in routine clinical practice.
methodsPatients with knee osteoarthritis (136) were evaluated. NP was assessed using the painDETECT questionnaire, with scores ≥ 13 categorized as NP( +). CS was assessed using the Central Sensitization Inventory (CSI), with scores ≥ 30 classified as CS( +). Pain intensity was measured at rest and during exercise using the visual analogue scale. Patients were grouped into low-pain and high-pain categories based on the average visual analogue scale score of pain at rest. Radiographic severity was assessed using the Kellgren-Lawrence grading system, classifying patients into low-grade (II–III) and high-grade (IV) categories. Demographic data, pain intensity, radiographic severity, painDETECT, and CSI scores were compared between the low- and high-pain intensity, low- and high-grade severity, NP( +) and NP( −), and CS( +) and CS( −) groups.
resultsNP and CS were identified in 15.4% and 16.2% of patients, respectively, and either NP or CS mechanisms were observed in 25.6%. CSI scores were higher in the high-pain group, and pain at rest was significantly higher in NP( +) and CS( +) groups.
conclusionsEither NP or CS mechanisms were identified in 25.6% of patients with knee OA. Higher pain at rest was associated with NP and CS, particularly CS, in this cohort.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.