Evidence map›Paper›PMID 42032525›Full record

ArticleBMC gastroenterology2026

Short‑ and long‑term prognostic factors of non‑neoplastic esophageal fistula: a retrospective study of 100 patients.

Qijie Dai, Yitian Wang, Xian Zhao, Weipeng Lu, Jiepeng Cen, Heqing Tao, Liang Peng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qijie DaiDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Yitian WangDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Xian ZhaoDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Weipeng LuDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Jiepeng CenDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China.
Heqing TaoDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China. tao_heqing@bjmu.edu.cn.
Liang PengDepartment of Gastroenterology, The Key Laboratory of Advanced Interdisciplinary Studies Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510120, China. wsfirefly@126.com.

Funding

Clinical Research Fund of Guangdong Medical Association 2024HY-B5003Natural Science Foundation of Guangdong Province 2021A1515110491Science and Technology Planning Project of Guangzhou City 2023A03J0339
6 · The paper itself

Abstract

purposeThis study examines the effects of different treatments on the prognosis of non-malignant esophageal fistula, a rare but serious condition, and identifies factors affecting post-fistula survival and healing.

methodsThis study retrospectively analyzed clinical data of patients with non-malignant esophageal fistula, categorizing them into conservative, endoscopic, and surgical groups. It compared Clinical Pulmonary Infection Score (CPIS) gap, hospital stay length, ICU admission, 30-day readmission, in-hospital and 90-day mortality rates, and hospitalization costs among these groups, while also assessing factors influencing post-fistula survival and healing.

results100 patients were included. Those who had surgery experienced longer hospital stays (P < 0.001), higher ICU occupancy rates (P = 0.006), and increased costs (P = 0.001) compared to others. Patients treated conservatively had a higher 30-day readmission rate (P = 0.018). Post-fistula survival and healing were unaffected by the primary treatment approach. Multivariate Cox regression indicated that smaller fistulas (P = 0.048), nasojejunal tube (P = 0.045), and thoracic drainage tube (P = 0.035) were favorable factors for fistula healing, while a lower BMI (P = 0.026) negatively impacted post-fistula survival.

conclusionEndoscopic treatment showed better short-term outcomes than the other groups, though it didn’t significantly improve post-fistula survival and healing. Several factors significantly impact the prognosis of esophageal fistula patients, requiring careful consideration in clinical practice.

Indexed as

Esophageal FistulaAdultAgedConservative TreatmentEsophagoscopyFemaleHumansLength of StayMaleMiddle AgedPatient ReadmissionPrognosisRetrospective StudiesEndoscopic treatmentNon-neoplastic esophageal fistulaOutcomesRetrospective studySurgical treatment

Identifiers

PMID42032525
PMCPMC13262301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.