ArticleBMC infectious diseases2026
Rickettsia typhi seroprevalence among patients with unexplained acute fever at the Sourô Sanou University Hospital Center (SSUHC), Burkina Faso.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate the seroprevalence of anti-IgG antibodies against Rickettsia typhi among patients with unexplained acute fever (UAF) at the Sourô Sanou University Hospital (CHUSS) in Bobo-Dioulasso, Burkina Faso.
methodsA prospective study was conducted from July to October 2025. A total of 87 patients with UAF were enrolled. The diagnostic protocol systematically included blood cultures and ELISA for the detection of anti-R. typhi IgG antibody. The diagnostic protocol included routine screening for malaria and dengue fever, as well as blood cultures. ELISA was performed only if the initial tests were negative.
resultsThe overall anti-R. typhi IgG antibody seroprevalence was 12.64% (12/87). The 30–45-year age group was the most represented (25.29%). Farmers and housemaids were the most exposed (18.2%). Clinically, chills and headaches were the most frequent symptoms (18.2%). Regarding risk factors, 54.5% of seropositive patients were reported living in proximity to animals or arthropod habitats. While 92% of blood cultures were negative, a statistically significant association was observed between serological and blood culture results (p < 0.001).
conclusionThese findings confirm the circulation of Rickettsia typhi in Bobo-Dioulasso, highlighting murine typhus as a potential cause of unexplained acute fever. However, the detection of anti- R. typhi IgG antibody can indicate past exposure; further studies using molecular technique or paired-sera analysis are essential to confirm acute cases and accurately assess the disease burden in Burkina Faso. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.